This directory contains a sorted and bgzip-compressed VCF (Variant Call Format) file containing all germline variations from the current Ensembl release for this species, named Homo_sapiens.vcf.gz. A file including the consequences of the variations on the Ensembl transcriptome, as called by the variation consequence pipeline, can be found in a file called Homo_sapiens_incl_consequences.vcf.gz. For human we also provide a file containing all somatic mutations in the database. The data contained in these files is presented in VCF format. For more details about the format refer to: http://www.1000genomes.org/wiki/analysis/variant-call-format/vcf-variant-call-format-version-42 Questions about these files can be addressed to the Ensembl helpdesk: helpdesk@ensembl.org, or to the developer's mailing list: dev@ensembl.org. -----