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Antibacterials

Class Drug
Cell wall biosynthesis inhibitor Penicillin binding protein inhibitor Penam (DG01480) Extended spectrum penicillin (DG01780) Ampicillin (DG00517), Pivampicillin (DG00518), Carbenicillin (DG00519), Amoxicillin (DG00520), Carindacillin (DG00521), Bacampicillin (DG00522), Epicillin (D04020), Pivmecillinam (DG00523), Azlocillin (DG00524), Mezlocillin (DG00525), Amdinocillin (D02888), Piperacillin (DG00526), Ticarcillin (DG00527), Metampicillin (DG00528), Talampicillin (DG00529), Sulbenicillin (DG00530), Temocillin (DG00531), Hetacillin (DG00532), Aspoxicillin (DG00533)
beta-Lactamase sensitive penicillin (DG01778) Benzylpenicillin (DG00534), Phenoxymethylpenicillin (DG00535), Propicillin (DG00536), Azidocillin (DG00537), Pheneticillin (DG00538), Penamecillin (D05406), Clometocillin (DG00539)
beta-Lactamase resistant penicillin (DG01779) Dicloxacillin (DG00540), Cloxacillin (DG00541), Meticillin (D02196), Oxacillin (DG00542), Flucloxacillin (DG00543), Nafcillin (DG00544)
Other penicillin Carfecillin (DG00443), Lenampicillin (DG01432), Tobicillin (D01214), Ciclacillin (D01334), Apalcillin (D02415), Fumoxicillin (D04270), Levopropylcillin (D04719), Penamecillin (D05406), Pirbenicillin (D05494), Piridicillin (D05496), Sarmoxicillin (D05805), Sarpicillin (D05806), Suncillin (D05974), Thiphencillin (D06113)
Cephem (DG01488) First-generation cephalosporin (DG01774) Cefalexin (DG00548), Cefaloridine (D01075), Cefalotin (DG00549), Cefazolin (DG00550), Cefadroxil (DG00551), Cefazedone (D07237), Cefatrizine (DG00552), Cefapirin (DG00553), Cefradine (D00264), Cefacetrile (DG00554), Cefroxadine (DG00555), Ceftezole (DG00556)
Second-generation cephalosporin (DG01775) Cefoxitin (DG00557), Cefuroxime (DG00558), Cefamandole (DG00559), Cefaclor (DG00560), Cefotetan (DG00561), Cefonicid (DG00562), Cefotiam (DG00563), Cefmetazole (DG00565), Cefprozil (DG00566), Ceforanide (D00259), Cefminox (DG00567), Cefbuperazone (DG00568)
Third-generation cephalosporin (DG01776) Cefotaxime (DG00570), Ceftazidime (DG00571), Cefsulodin (DG00572), Ceftriaxone (DG00573), Cefmenoxime (DG00574), Ceftizoxime (DG00576), Cefixime (DG00577), Cefodizime (DG00578), Cefetamet (DG00579), Cefpiramide (DG00580), Cefoperazone (DG00581), Cefpodoxime (DG00582), Ceftibuten (DG00583), Cefdinir (D00917), Cefditoren (DG00584), Cefcapene (DG00585)
Fourth-generation cephalosporin (DG01777) Cefepime (DG00586), Cefpirome (DG00587), Cefozopran (DG00588)
Other cephalosporin Cefaloglycin (DG01205), Cefoselis (DG01206), Cefpimizole (DG01207), Cefteram (DG01208), Ceftobiprole (DG01209), Ceftolozane (DG01210), Cefuzonam (DG01211), Cefquinome (DG01433), Ceftiofur (DG01434), Cefluprenam (D01054), Cefovecin (D01681), Cefmatilen (D01961), Cefaparole (D03421), Cefazaflur (D03422), Cefetecol (D03425), Cefalonium (D07634), Ceftaroline (D08884)
Carbacephem (DG01711) Second-generation cephalosporin Loracarbef (DG00564)
Oxacephem (DG01459) Flomoxef (DG00569)
Third-generation cephalosporin Latamoxef (DG00575)
Penem (DG01486) Faropenem (DG00594), Sulopenem (DG01213)
Carbapenem (DG01458) Meropenem (DG00591), Ertapenem (DG00592), Doripenem (DG00593), Biapenem (D01057), Imipenem (DG01212), Panipenem (D01048), Lenapenem (D01058), Tomopenem (D09022), Tebipenem (D09598), Razupenem (D09658), Ritipenem (D09849)
Monobactam (DG01454) Aztreonam (DG00589), Carumonam (DG00590), Oximonam (DG01263), Pirazmonam (D05492), Tigemonam (D06144), Gloximonam (D04328)
Beta-lactamase inhibitor (DG01479) Penicillin Sulbactam (DG00545), Tazobactam (DG00546), Sultamicillin (DG00547)
Clavam (DG01487) Clavulanic acid (DG01261)
Other Avibactam (D10340)
Peptidoglycan biosynthesis inhibitor Glycopeptide (DG01580) Vancomycin (DG00086), Teicoplanin (D02142), Telavancin (D06057), Dalbavancin (D03640), Oritavancin (DG00632), Actaplanin (D02782), Avoparcin (D03016), Ramoplanin (D05696)
Other UDP-N-acetylglucosamine 1-carboxyvinyltransferase inhibitor Fosfomycin (DG00633)
enoyl-[acyl-carrier-protein) reductase (NADH) inhibitor Isoniazid (DG00642)
alanine racemase inhibitor Cycloserine (D00877)
D-alanine-D-alanine ligase inhibitor Cycloserine (D00877)
arabinosyltransferase inhibitor Ethambutol (DG00643)
Protein biosynthesis inhibitor 16S rRNA of 30S ribosomal subunit inhibitor Tetracycline (DG01197) Tetracycline (DG00005), Chlortetracycline (DG00007), Doxycycline (DG00008), Minocycline (DG00009), Demeclocycline (DG00396), Oxytetracycline (DG00397), Meclocycline (DG00437), Lymecycline (D06884), Metacycline (DG00514), Rolitetracycline (DG00515), Clomocycline (D06885), Tigecycline (D01079), Omadacycline (DG01198), Eravacycline (DG01199), Amicycline (D02899), Cetocycline (D03451), Demecycline (D03681), Nitrocycline (D05184), Penimepicycline (D07233), Sancycline (D05796)
Aminoglycoside (DG01447) Neomycin (DG00003), Streptomycin (DG00082), Paromomycin (DG00084), Kanamycin (DG00085), Gentamicin (DG00401), Amikacin (DG00403), Tobramycin (DG00608), Netilmicin (DG00609), Sisomicin (DG00610), Dibekacin (DG00611), Ribostamycin (DG00612), Isepamicin (DG00613), Arbekacin (DG00614), Bekanamycin (DG00615), Spectinomycin (DG00634), Dihydrostreptomycin (DG01122), Micronomicin (DG01123), Astromicin (DG01200), Framycetin (DG01446), Apramycin (D02322), Betamicin (D03104), Butikacin (D03190), Fidaxomicin (D09394), Nebramycin (D05128), Pentisomicin (D05425), Plazomicin (D10151), Propikacin (D05629), Streptoduocin (D07432), Trospectomycin (D06254)
23S rRNA of 50S ribosomal subunit inhibitor Macrolide (DG01551) Erythromycin (DG00436), Spiramycin (DG00602), Oleandomycin (DG00603), Josamycin (DG00604), Clarithromycin (DG00605), Azithromycin (DG00606), Midecamycin (DG01202), Kitasamycin (DG01203), Tilmicosin (DG01435), Tylosin (DG01436), Rosaramicin (DG01513), Cethromycin (D02391), Dirithromycin (D03865), Flurithromycin (D07242), Gamithromycin (D06598), Lexithromycin (D04725), Megalomicin (D04896), Midecamycin (D01636), Modithromycin (D09642), Neutramycin (D05153), Relomycin (D05713), Rokitamycin (D01897), Roxithromycin (D01710), Repromicin (D05717), Sedecamycin (D05811), Solithromycin (D09965), Telithromycin (D01078), Troleandomycin (D01322), Tulathromycin (D06258)
Lincosamide (DG01578) Clindamycin (DG00435), Lincomycin (DG00607), Pirlimycin (DG01577), Mirincamycin (D05049)
Amphenicol (DG01576) Chloramphenicol (DG00399), Thiamphenicol (DG00516), Azidamfenicol (D07411), Cetophenicol (D03452), Florfenicol (D04194), Racephenicol (D05687)
Pleuromutilin derivative (DG01813) Tiamulin (DG01437), Valnemulin (DG01438), Retapamulin (D05720)
Other Nosiheptide (D02392), Thiostrepton (D06111)
50S ribosomal subunit inhibitor Oxazolidinone (DG01789) Radezolid (DG01441), Tedizolid (DG01442), Eperezolid (D04017), Linezolid (D00947), Sutezolid (D10167)
Other Evernimicin (D04119)
Isoleucyl-tRNA synthetase (IARS) inhibitor Mupirocin (DG00402)
Methionyl-tRNA synthetase (MetRS) inhibitor Bederocin (D09324)
Other Steroid Fusidic acid (DG00398)
Streptogramin Dalfopristin (D00853), Mikamycin B (C11615), Pristinamycin (C11616), Quinupristin (D00852)
Peptide Capreomycin (DG00641), Enviomycin (DG01219), Viomycin
Other Puromycin (DG01220)
Folic acid biosynthesis inhibitor Dihydropteroate synthase inhibitor Sulfonamide (DG01787) Mafenide (DG00404), Sulfadimidine (DG00597), Sulfafurazole (DG00598), Sulfadiazine (DG00599), Sulfadimethoxine (DG00600), Sulfamethoxypyridazine (DG00601), Succinylsulfathiazole (DG00088), Sulfacetamide (DG01124), Sulfamonomethoxine (DG01204), Acetylsulfamethoxazole (D01601), Acetylsulfisoxazole (D05956), Phthalylsulfathiazole (D02440), Sulfachlorpyridazine (D05948), Sulfaguanidine (D02437), Sulfamethizole (D00870), Sulfamethoxazole (D00447), Sulfamerazine (D02435), Sulfamethopyrazine (D01216), Sulfametomidine (D02450), Sulfametoxydiazine (D02517), Sulfamoxole (D02516), Sulfamazone (D07241), Sulfanilamide (D08543), Sulfaperin (D07240), Sulfaphenazole (D01954), Sulfapyridine (D02434), Sulfaquinoxaline (D05952), Sulfathiazole (D01047), Sulfathiourea (D07239), Sulfisomidine (D01526)
Other Dapsone (D00592), Glucosulfone (D02520)
Dihydrofolate reductase inhibitor Trimethoprim derivative (DG01581) Trimethoprim (DG00595), Iclaprim (DG00596), Brodimoprim (D07238), Metioprim (D05005), Ormetoprim (D05273), Tetroxoprim (D06097)
Nucleic acid synthesis inhibitor Type II topoisomerase (DNA gyrase topoisomerase IV) inhibitor Fluoroquinolone (DG01549) Ofloxacin (DG00616), Ciprofloxacin (DG00617), Pefloxacin (DG00618), Enoxacin (DG00619), Norfloxacin (DG00620), Lomefloxacin (DG00621), Rufloxacin (DG00622), Grepafloxacin (DG00623), Levofloxacin (DG00624), Trovafloxacin (DG00625), Moxifloxacin (DG00626), Gemifloxacin (DG00627), Gatifloxacin (DG00628), Pazufloxacin (DG00629), Alatrofloxacin (DG01214), Delafloxacin (DG01215), Sarafloxacin (DG01216), Tosufloxacin (DG01217), Amifloxacin (DG01226), Danofloxacin (DG01227), Difloxacin (DG01228), Balofloxacin (D02463), Clinafloxacin (D02539), Enrofloxacin (D02473), Fleroxacin (D01716), Garenoxacin (D02540), Orbifloxacin (D08299), Premafloxacin (D05605), Prulifloxacin (D01144), Sitafloxacin (D02475), Sparfloxacin (D00590), Temafloxacin (D02469), Binfloxacin ( D03118), Ibafloxacin (D04485), Marbofloxacin (D08156), Besifloxacin (D08872), Cadrofloxacin (D09782), Olamufloxacin (D09840), Avarofloxacin (D10435)
Other quinolone (DG01550) Enoxacin (DG00619), Nalidixic acid (DG00630), Pipemidic acid (DG00631), Cinoxacin (D00872), Droxacin (D02467), Fleroxacin (D01716), Flumequine (D02302), Miloxacin (D02303), Oxolinic acid D02301), Ozenoxacin (D09544), Piromidic acid (D01431), Rosoxacin (D02305), Tioxacin (D02468)
Other Coumermycin (DG01443), Novobiocin (D01209), Olaquindox (D08292)
RNA polymerase inhibitor Rifamycin (DG01598) Rifampicin (DG00639), Rifamycin (DG00640), Rifabutin (D00424), Rifalazil (D02550), Rifametane (D02551), Rifamexil (D02552), Rifamide (D02553), Rifapentine (D00879), Rifaximin (D02554)
Other Cell membrane function inhibitor Polypeptide (DG01579) Polymyxin B (DG00083), Colistin (DG00087), Bacitracin (DG00400), Amphomycin (D02927), Surotomycin (D10380)
Peptide Gramicidin (DG01043)
Lipopeptide Daptomycin (D01080)
Other Polyether ionophore Monensin (DG01221), Semduramicin (DG01222), Laidlomycin (D04658), Lasalocid (D04671), Maduramicin (D04830), Narasin (D05122), Salinomycin(D08502)
Hydantoin type nitrofuran (DG01552) Nifurtoinol (D00439), Nitrofurantoin (D07243), Furazidin (D07998),
5-Nitrofuran (DG01553) Furaltadone (D02510), Furalazine (D02511), Furazolidone (D00830), Levofuraltadone (D04714), Nifuradene (D02514), Nifurpirinol (D02513), Nifuraldezone (D05159), Nifuratel (D01050), Nifuratrone (D05160), Nifurdazil (D05161), Nifurimide (D05162), Nifuroxazide (D07111), Nifurquinazol (D05164), Nifurstyrenate (D02538), Nifurthiazole (D05167), Nifurzide (D07251), Nitrofurazone (D00862)

Antifungals

Class Drug
Cell wall biosyntehsis inhibitor beta-13-glucan synthase inhibitor Echinocandin Caspofungin (DG00636), Micafungin (DG00637), Anidulafungin (D03211), Cilofungin(D03500)
Ergosterol biosynthesis inhibitor sterol 14alpha-demethylase inhibitor Imidazole Miconazole (DG00004), Econazole (DG00363), Chlormidazole (DG00364), Isoconazole (DG00365), Sulconazole (DG00366), Oxiconazole (DG00367), Fenticonazole (DG00368), Omoconazole (DG00369), Sertaconazole (DG00370), Butoconazole (DG00444), Eberconazole (DG00372), Croconazole (DG01297), Bifonazole (D01775), Cisconazole (D03526), Clotrimazole (D00282), Doconazole (D03883), Enilconazole (D03997), Flutrimazole (D07193), Ketoconazole (D00351), Lanoconazole (D01092), Luliconazole (D01980), Neticonazole (D01620), Orconazole (D05268), Parconazole (D05367), Tioconazole (D00890), Zinoconazole (D06373)
Triazole (DG01523) Fluconazole (DG00371), Albaconazole (D09702), Alteconazole (D02586), Azaconazole (D03023), Efinaconazole (D10021), Itraconazole (D00350), Posaconazole (D02555), Pramiconazole (D06630), Ravuconazole (D02556), Saperconazole (D05800), Terconazole (D00888), Vibunazole (D02585)), Voriconazole (D00578)
squalene epoxidase inhibitor Thiocarbamate Liranaftate (D01550), Tolciclate (D01384), Tolnaftate (D00381)
Allylamine Terbinafine (DG00375), Naftifine (DG00377)
Benzylamine Butenafine (DG00378)
Morpholine Amorolfine (DG00376)
Other Cell membrane function inhibitor Polyene macrolide Amphotericin B (D00203), Nystatin (D00202), Pimaricin (D00884), Trichomycin (D02143)
Nucleic acid synthesis inhibitor Fluoropyrimidine Flucytosine (D00323)

Antivirals

Class Drug
Anti-CMV agent Translation inhibitor Antisense oligonucleotide Fomivirsen (DG01125)
DNA polymerase inhibitor Purine analogue Ganciclovir (DG00646), Valganciclovir (DG00649), Maribavir (D04859)
Nucleotide analogue Cidofovir (D00273)
Phosphonic acid derivative Foscarnet (DG00651), Fosfonet (D04254)
Anti-HBV agent Reverse transcriptase inhibitor (RTI) Nucleoside and nucleotide reverse transcriptase inhibitor (NRTI) Entecavir (DG00661), Adefovir (DG01224), Amdoxovir (D02890), Clevudine (D03537), Lamivudine (D00353), Elvucitabine (D03981), Telbivudine (D06675)
Anti-HCV agent Protease inhibitor (PI) NS3/NS4A protease inhibitor Simeprevir (DG01246), Telaprevir (D09012)
NS3 protease inhibitor Asunaprevir (D10093), Sovaprevir (D10166)
Polymerase inhibitor NS5A polymerase inhibitor Daclatasvir (DG01669)
NS5B polymerase inhibitor Filibuvir (D09616), Nesbuvir (D08951), Setrobuvir (D10165), Sofosbuvir (D10366), Tegobuvir (D09971)
Glycoprotein processing inhibitor alpha-glucosidase I inhibitor Celgosivir (D03433)
Other Nucleoside Ribavirin (D00423), Taribavirin (D06651), Valopicitabine (D09028)
Anti-HIV agent Entry / fusion inhibitor CD4 antibody Ibalizumab (D09575)
chemokine receptor 5 inhibitor(CCR5) antagonist Ancriviroc (D03210), Aplaviroc (D06557), Cenicriviroc (DG01264), Maraviroc (D06670), Vicriviroc (D06297)
HIV glycoprotein 41 (gp41) inhibitor Enfuvirtide (D02499)
Reverse transcriptase inhibitor (RTI) Nucleoside and nucleotide reverse transcriptase inhibitor (NRTI) Abacavir (DG00660), Tenofovir (DG01223), Amdoxovir (D02890), Emtricitabine (D01199), Elvucitabine (D03981), Dexelvucitabine (D06580), Didanosine (D00296), Lamivudine (D00353), Sanilvudine (D00445), Zalcitabine (D00412), Zidovudine (D00413)
Non-nucleoside reverse transcriptase inhibitor (NNRTI) Delavirdine (DG00662), Rilpivirine (DG00663), Efavirenz (D00896), Emivirine (D00896), Etravirine (D04112), Loviride (D04786), Nevirapine (D00435)
Protease inhibitor (PIs) Peptidic Saquinavir (DG00653), Indinavir (DG00654), Droxinavir (D03839), Lopinavir (D01425), Palinavir (D03840), Ritonavir (D00427), Telinavir (D03842)
Aza-peptidic Atazanavir (DG00657)
Nonpeptidic Nelfinavir (DG00655), Fosamprenavir (DG00656), Tipranavir (DG00658), Darunavir (DG00659), Amprenavir (D00894), Brecanavir (D03253), Mozenavir (D05538)
Other HIV-1 integrase inhibitor Raltegravir (DG00666), Dolutegravir (DG00667), Elvitegravir (D06677)
HIV maturation inhibitor Bevirimat (D06564)
Anti-HSV agent Entry / fusion inhibitor Saturated fatty alcohol Docosanol (D03884)
DNA polymerase inhibitor Purine analogue Aciclovir (DG00406), Penciclovir (DG00408), Valacyclovir (DG00647), Famciclovir (D00317), Desciclovir (D03690)
Pyrimidine analogue Vidarabine (DG00645), Idoxuridine (D00342), Sorivudine (D01734), Trifluridine (D00391)
Anti-influenza agent Uncoating inhibitor influenza A M2 proton channel blocker Amantadine (DG00860), Rimantadine (DG00650)
influenzavirus A/B neuraminidase inhibitor Zanamivir (DG00664), Oseltamivir (DG00665), Laninamivir (DG01201), Peramivir (D03829)
Other Anti-HRV agent HRV 3C protease inhibitor Rupintrivir (D05776)
Anti-HPV agent human papillomavirus E2 antisense Afovirsen (D02783)
Anti-RSV agent Anti-RSV F protein monoclonal antibody Palivizumab (D02737)
DNA polymerase inhibitor Purine analogue Lobucavir (D04757)

Antiparasitics

Class Drug
Antmalarial dihydrofolate reductase inhibitor Biguanide Proguanil (DG01018), Cycloguanil embonate (D02387)
Diaminopyrimidine Pyrimethamine (D00488)
sarcoplasmic/endoplasmic-reticulum Ca2+-ATPase (SERCA) inhibitor Artemisinin and derivative Artemisinin (D02481), Artemether (D02483), Artesunate (D02482), Artemotil (D07361), Artenimol (D07362)
Other Aminoquinoline Chloroquine (DG01014), Hydroxychloroquine (DG01015), Primaquine (DG01016), Amodiaquine (DG01017)
Methanolquinoline Quinine (DG01019), Mefloquine (DG01020), Halofantrine (DG01021)
Agent against Leishmaniasis and Trypanosomiasis Nitroimidazole derivative Benznidazole (D02489)
Nitrofuran derivative Nifurtimox (D00833), Nitrofural (D00862)
Antimony compound Meglumine antimonate (D02491), Sodium stibogluconate (D00582)
Arsenic compound Acetarsol (D07110), Melarsoprol (D00832)
Other Eflornithine (DG00440), Pentamidine isethionate (D00834), Suramin sodium (D00808), Miltefosine (D02494)
Agent against Amebiasis and other antiprotozoal Hydroxyquinoline derivative Broxyquinoline (D07109), Clioquinol (D03538), Chlorquinaldol (D07208), Tilbroquinol (D07351)
Nitroimidazole derivative Metronidazole (DG00006), Azanidazole (D03028), Nimorazole (D07352), Ornidazole (D05274), Propenidazole (D07430), Secnidazole (D07353), Tinidazole (D01426)
Dichloroacetamide derivative Diloxanide (DG01010), Clefamide (D07354), Etofamide (D07355), Teclozan (D06051)
Arsenic compound Arsthinol (D07356), Difetarsone (D07357), Glycobiarsol (D07358)
Other Emetine (DG01011), Mepacrine (DG01012), Trimetrexate (DG01013), Atovaquone (D00236), Chiniofon (D07438), Dehydroemetine (D00828), Nitazoxanide (D02486), Phanquinone (D07359), Tenonitrozole (D07360)
Antitrematodal agent Quinoline derivative and related substance Oxamniquine (D00460), Praziquantel (D00471)
Organophosphorous compound Metrifonate (D00805)
Other Bithionol (DG00432), Niridazole (D05170), Stibophen (D07363), Triclabendazole (D07364)
Antinematodal agent Benzimidazole derivative Albendazole (DG01022), Ciclobendazole (D03623), Fenbendazole (D04140), Flubendazole (D04200), Mebendazole (D00368), Tiabendazole (D00368)
Piperazine and derivative Piperazine (DG01023), Diethylcarbamazine (DG01024)
Tetrahydropyrimidine derivative Pyrantel (DG01025), Oxantel (D00806)
Imidazothiazole derivative Levamisole (DG01026)
Avermectine Ivermectin (D00804)
Other Pyrvinium (DG01027)
Anticestodal agent Salicylic acid derivative Niclosamide (D00436)
Other Desaspidin (D07365)

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Last updated: March 9, 2015