KEGG DRUG: New Drug Approvals in Japan

Date	KEGG	ATC	JTC*	Active ingredient	Drug name	Company	Remark
2017/7/3	D10791		1190	Nusinersen sodium	Spinraza	Biogen Japan	D10881
2017/7/3	D06637	L01XX39	4291	Romidepsin	Istodax	Celgene
2017/7/3	D05589	L01BA05	4229	Pralatrexate	Difolta	Mundipharma
2017/7/3	D10564		6250	Amenamevir	Amenalief	Maruho	NME
2017/7/3	D10308	L04AA37	3999	Baricitinib	Olumiant	Lilly
2017/7/3	D10711		2183	Pemafibrate	Parmodia	Kowa	NME
2017/3/30	D10884		6343	Human prothrombin complex, freeze-dried concentrated	Kcentra	CSL Behring
2017/3/30	D10131	L01XX50	4291	Ixazomib citrate	Ninlaro	Takeda	NME
2017/3/30	D04245		4291	Forodesine hydrochloride	Mundesine	Mundipharma
2017/3/30	D10819		4291	Aflibercept beta (genetical recombination)	Zaltrap	Sanofi
2017/3/30	D00839	N02AA03	8119	Hydromorphone hydrochloride	Narusus, Narurapid	DaiichiSankyo-pp
2017/3/30	D10478		2359	Naldemedine tosylate	Symproic	Shionogi	NME
2017/3/30	D00606	C02AC02	1179	Guanfacine hydrochloride	Intuniv	Shionogi
2016/12/19	D03846	N07XX09	1190	Dimethyl fumarate	Tecfidera	Biogen	NME
2016/12/19	D10605	J05AF13	6250	Tenofovir alafenamide fumarate	Vemlidy	Gilead Sciences
2016/12/19	D08860	L04AA32	3999	Apremilast	Otezla	Celgene	NME
2016/12/19	D02484	P01BF01	6419	Artemether - lumefantrine mixt	Riamet	Novartis Pharma	NME
2016/12/19	D09355	A06AX04	2390	Linaclotide	Linzess	Astellas Pharma	NME
2016/12/19	D09617	V09AX05		Florbetapir F-18	Amyvid	Fujifilm RI Pharma	NME
2016/12/19	D08971	L03AX16	3399	Plerixafor	Mozobil	Sanofi	NME
2016/12/19	D10677	H05BX04	3999	Etelcalcetide hydrochloride	Parsabiv	Ono pharmaceutical	NME
2016/12/19			6250	Daclatasvir - asunaprevir - beclabuvir mixt	Ximency	Bristol-Myers Squibb
2016/12/19	D10517			Crisantaspase	Erwinase	Ohara Pharmaceutical
2016/9/28	D10625		6250	Elbasvir	Erelsa	MSD	D10778
2016/9/28	D10639		6250	Grazoprevir	Grazyna	MSD	D10778
2016/9/28	D10741	V03AB37	3399	Idarucizumab	Prizbind	Boehringer Ingelheim	BLA
2016/9/28	D07130	A16AA05	3999	Carglumic acid	Carbaglu	POLA-Pharma	NME
2016/9/28	D09951	L01XE24	4291	Ponatinib hydrochloride	Iclusig	Otsuka Pharmaceutical	NME
2016/9/28	D09638	C10AX12	2189	Lomitapide mesylate	Juxtapid	Aegerion Pharmaceuticals	NME
2016/9/28	D09994	B01AC27	2190	Selexipag	Uptravi	Nippon Shinyaku	NME
2016/9/28	D02554	A07AA11 D06AX11	6199	Rifaximin	Rifxima	ASKA Pharmaceutical	NME
2016/9/28	D09337		4291	Elotuzumab	Empliciti	Bristol-Myers Squibb	BLA
2016/9/28	D10574	L01XC18	4291	Pembrolizumab	Keytruda	MSD	BLA
2016/9/28	D10770		6349	Albutrepenonacog alfa	Idelvion	CSL Behring	BLA
2016/9/28	D09570	R06AX29	4490	Bilastine	Bilanoa	Taiho Pharmaceutical	NME
2016/9/28	D03693	R06AX27	4490	Desloratadine	Desalex	MSD	NME
2016/9/28	D03478	G03GA08	2413	Choriogonadotropin alfa	Ovidrel	Merck Serono
2016/9/28	D09017	B01AC24	3399	Ticagrelor	Brilinta	AstraZeneca	NME
2016/9/28	D10566	H01CB05	2499	Pasireotide pamoate	Signifor LAR	Novartis Pharma	D10497
2016/7/4	D00533	N03AF02		Oxcarbazepine	Ocnobel	Nobelpharma
2016/7/4	D08880	L01XX45	4291	Carfilzomib	Kyprolis	Ono Pharmaceutical	NME
2016/7/4	D07299	N03AX18	1139	Lacosamide	Vimpat	UCB Japan	NME
2016/7/4	D10335		2189	Alirocumab	Praluent	Sanofi	BLA
2016/7/4	D10071		3999	Ixekizumab	Taltz	Eli Lilly Japan	BLA
2016/7/4	D10061	L04AC12	3999	Brodalumab	Lumicef	Kyowa Hakko Kirin	BLA
2016/6/17	D10755	J05AR18	6250	Elvitegravir - cobicistat - emtricitabine - tenofovir alafenamide mixt	Genvoya	Japan Tobacco	NME
2016/3/28	D02995	N05AH05	1179	Asenapine maleate	Sycrest	Meiji Seika Pharma	NME
2016/3/28	D10223	L01XE27	4291	Ibrutinib	Imbruvica	Janssen Pharmaceutical	NME
2016/3/28	D10398	V10XX03	4291	Radium-223 dichloride	Xofigo	Bayer Yakuhin	NME
2016/3/28	D10771		6349	Octocog beta	Kovaltry	Bayer Yakuhin
2016/3/28	D10766		4291	Osimertinib mesylate	Tagrisso	AstraZeneca	NME
2016/3/28	D10377	A16AB14	3959	Sebelipase alfa	Kanuma	Alexion Pharma	BLA
2016/3/28	D10551	L01XE28	4291	Ceritinib	Zykadia	Novartis Pharma	NME
2016/3/28	D10104	L01XE23	4291	Dabrafenib mesylate	Tafinlar	Novartis Pharma	NME
2016/3/28	D10176	L01XE25	4291	Trametinib dimethyl sulfoxide	Mekinist	Novartis Pharma	NME
2016/3/28	D00535	N03AG04	1139	Vigabatrin	Sabril	Sanofi	NME
2016/3/28	D02126	P01BA03	6419	Primaquine phosphate	Primaquine	Sanofi
2016/3/28	D10780	N03AX22	1139	Perampanel hydrate	Fycompa	Eisai	NME
2016/3/28	D04923	R03DX09	2290	Mepolizumab	Nucala	GlaxoSmithKline	BLA
2016/3/28	D10760		6349	Rurioctocog alfa pegol	Adynovate	Baxter (Baxalta)
2016/1/22	D10557	C10AX13	2189	Evolocumab	Repatha	Astellas Pharma	BLA
2016/1/22				Haemophilus influenzae type b (Hib) conjugate vaccine	Vaxem Hib	Takeda Pharmaceutical
2016/1/22	D03106	L01XX25	4291	Bexarotene	Targretin	Minophagen Pharmaceutical	NME
2016/1/22	D04970		7290	Methacholine chloride	Kenbran, Provocholine	Santen Pharmaceutical, Sanwa Kagaku Kenkyusho
2015/9/28	D09544		2639	Ozenoxacin	Zebiax	Maruho	NME
2015/9/28	D10744	R03BB54	2259	Tiotropium - olodaterol mixt	Spiolto	Boehringer Ingelheim	mixture
2015/9/28	D06407	L01XE12	4291	Vandetanib	Caprelsa	AstraZeneca	NME
2015/9/28	D10476		3399	Lusutrombopag	Mulpleta	Shionogi	NME
2015/9/28	D02721	B01AC11	2190	Iloprost	Ventavis	Bayer	NME
2015/9/28	D00821	N06AX16	1179	Venlafaxine hydrochloride	Effexor	Pfizer
2015/9/28	D04318	L03AX13	3999	Glatiramer acetate	Copaxone	Takeda Pharmaceutical
2015/9/28	D10317		3969	Omarigliptin	Marizev	MSD
2015/9/28	D06199	L01CX01	4291	Trabectedin	Yondelis	Taiho Pharmaceutical	NME
2015/9/28	D10746		2649	Esflurbiprofen - mentha oil mixt	Loqoa	Taisho Pharmaceutical
2015/9/28	D10745		6250	Ombitasvir - paritaprevir -ritonavir mixt	Viekirax	AbbVie
2015/9/28	D02108	V09IB01	4300	Indium In 111 pentetreotide	Octreoscan	Fujifilm RI Pharma
2015/7/3	D10578		6250	Ledipasvir - sofosbuvir mixt	Harvoni	Gilead Sciences	NME
2015/7/3	D02114	P01BA02	3999	Hydroxychloroquine sulfate	Plaquenil	Sanofi
2015/7/3	D10396		3999	Nintedanib esylate	Ofev	Boehringer Ingelheim
2015/7/3	D10684		6349	Antithrombin gamma	Acoalan	Kyowa Hakko Kirin	BLA
2015/7/3	D04603	L01XC11	4291	Ipilimumab	Yervoy	Bristol-Myers	BLA
2015/7/3	D10019	L01XX42	4291	Panobinostat lactate	Farydak	Novartis Pharma	NME
2015/7/3	D09596	M09AB02	2900	Collagenase clostridium histolyticum	Xiaflex	Asahi Kasei Pharma	BLA
2015/7/3	D09889		2499	Dulaglutide	Trulicity	Eli Lilly Japan	BLA
2015/7/3	D10595		3959	Asfotase alfa	Strensiq	Alexion Pharma	BLA
2015/7/3	D10451		2619	Olanexidine gluconate	Olanedine	Otsuka Pharmaceutical Factory	NME
2015/3/26	D10532		6343	Catridecacog	NovoThirteen	Novo Nordisk Pharma
2015/3/26	D09920		4291	Lenvatinib mesylate	Lenvima	Eisai	NME
2015/3/26	D09371		4291	Ramucirumab	Cyramza	Eli Lilly Japan	BLA
2015/3/26	D08976	L04AX06	4291	Pomalidomide	Pomalyst	Celgene	NME
2015/3/26	D10181	R03BB07	2259	Umeclidinium bromide	Encruse	GlaxoSmithKline
2015/3/26	D08837	R03BB05	2259	Aclidinium bromide	Eklira	Kyorin Pharmaceutical	NME
2015/3/26	D10135	C02KX04	2190	Macitentan	Opsumit	Actelion Pharmaceuticals Japan	NME
2015/3/26	D07420	V08CA09	7290	Gadobutrol	Gadovist	Bayer	NME
2015/3/26	D10366	J05AX15	6250	Sofosbuvir	Sovaldi	Gilead Sciences	NME
2015/3/26	D09894	A16AX10	3999	Eliglustat tartrate	Cerdelga	Genzyme Japan
2015/3/26	D10179		3969	Trelagliptin succinate	Zafatek	Takeda Pharmaceutical	NME
2014/12/26	D10538		6343	Nonacog gamma	Rixubis	Baxter
2014/12/26	D05177	A16AX04	3999	Nitisinone	Orfadin	Astellas Pharma	NME
2014/12/26	D10459	A10BX12	3969	Empagliflozin	Jardiance	Boehringer Ingelheim	NME
2014/12/26	D06405	V03AX02	1190	Nalfurafine hydrochloride	Nopicor	Toray Medical	NME
2014/12/26	D10466		2329	Vonoprazan fumarate	Takecab	Takeda Pharmaceutical	NME
2014/12/26	D10537	V03AB17 V04CG05	3929	Methylthioninium chloride hydrate	Methylene Blue	Daiichi Sankyo
2014/12/26	D03093	D10AE01	2699	Benzoyl peroxide	Bepio Gel	Maruho
2014/12/26	D10333	A16AB12	3959	Elosulfase alfa	Vimizim	BioMarin Pharmaceutical Japan	BLA
2014/12/26	D08770	V01AA20	4490	Allergen extract (therapeutic)	Allergen Extract for Subcutaneous Injection	Torii Pharmaceutical
2014/12/26	D08771	V01AA20	7290	Allergen extract (diagnostic)	Allergen Extract for Scratch Test	Torii Pharmaceutical
2014/12/26	D09967	L04AC10	3999	Secukinumab	Cosentyx	Novartis Pharma	BLA
2014/12/26	D10539		6349	Efraloctocog alfa	Eloctate	Biogen Idec Japan
2014/12/26	D09996	L01XE15	4291	Vemurafenib	Zelboraf	Chugai Pharmaceutical	NME
2014/9/26	D10082		1190	Suvorexant	Belsomra	MSD	NME
2014/9/26	D06889	L03AA13	3399	Pegfilgrastim	G-Lasta	Kyowa Hakko Kirin
2014/9/26	D10255	L01XX35	4299	Anagrelide hydrochloride hydrate	Agrylin	Shire Japan
2014/9/26	D10463		1319	Ripasudil hydrochloride hydrate	Glanatec	Kowa
2014/9/26	D00707	V03AB34	3929	Fomepizole	Fomepizole	Takeda Pharmaceutical
2014/9/26	D02802	L04AA34	4290	Alemtuzumab	MabCampath	Sanofi
2014/9/26	D09987		6250	Vaniprevir	Vanihep	MSD
2014/9/26	D09728	L01XE14	4291	Bosutinib hydrate	Bosulif	Pfizer	NME
2014/9/26	D05932	L01AD04	4219	Streptozocin	Zanosar	Nobelpharma
2014/7/4	D09592	A10BX11	3969	Canagliflozin	Canaglu	Mitsubishi Tanabe Pharm	NME
2014/7/4	D10021		6290	Efinaconazole	Clenafin	Kaken Pharmaceutical	NME
2014/7/4	D09785	J04AK06	6222	Delamanid	Deltyba	Otsuka Pharmaceutical	NME
2014/7/4	D10533	R03AL03	2259	Umeclidinium bromide - vilanterol mixt	Anoro	GlaxoSmithKline	NME
2014/7/4	D09701	L02BX03	4290	Abiraterone acetate	Zytiga	Janssen Pharmaceutical	NME
2014/7/4	D10452	L01CD04	4240	Cabazitaxel acetonate	Jevtana	Sanofi
2014/7/4	D10535	J07AH08	6311	Meningococcus A,C,Y,W-135, tetravalent purified polysaccharides antigen conjugated	Menactra	Sanofi
2014/7/4	D09960	L01XE18	4291	Ruxolitinib phosphate	Jakavi	Novartis Pharma	NME
2014/7/4	D10450		4291	Alectinib hydrochloride	Alecensa	Chugai Pharmaceutical	NME
2014/7/4			6343	Freeze-dried activated human blood coagulation factor VII concentrate containing factor X	Byclot	Chemo-Sero-Therapeutic Research Institute
2014/7/4	D00753	L04AA10	4291	Sirolimus	Rapalimus	Nobelpharma	NME
2014/7/4	D09029	A16AB10	3959	Velaglucerase alfa	Vpriv	Shire Japan
2014/7/4	D10468		3929	Cysteamine bitartrate	Nicystagon	Mylan	NME
2014/7/4	D10522		6343	Eftrenonacog alfa	Alprolix	Biogen Idec Japan
2014/7/4	D10105	J05AX14	6250	Daclatasvir dihydrochloride	Daklinza	Bristol-Myers	NME
2014/7/4	D10093	J05AE15	6250	Asunaprevir	Sunvepra	Bristol-Myers
2014/7/4	D10316		4291	Nivolumab	Opdivo	Ono Pharmaceutical	BLA
2014/3/24	D06213	B01AC21	2190	Treprostinil	Treprost	Mochida Pharmaceutical	NME
2014/3/24	D05597	B01AC22	3399	Prasugrel hydrochloride	Efient	Daiichi Sankyo	NME
2014/3/24	D06886	L04AA23	1190	Natalizumab	Tysabri	Biogen Idec Japan	BLA
2014/3/24	D10199	N02AX06	8219	Tapentadol hydrochloride	Tapenta	Janssen Pharmaceutical
2014/3/24	D09537		6250	Favipiravir	Avigan	Toyama Chemical	NME
2014/3/24	D01982	J05AF07	6250	Tenofovir disoproxil fumarate	Tenozet	GlaxoSmithKline	NME
2014/3/24	D09763	A10BX09	3969	Dapagliflozin propanediol	Forxiga	Bristol-Myers	NME
2014/3/24	D10195		3969	Luseogliflozin hydrate	Lusefi	Taisho Pharmaceutical	NME
2014/3/24	D09978		3969	Tofogliflozin	Deberza, Apleway	Kowa, Sanofi	NME
2014/3/24	D10526	L01BC59	4299	Trifluridine - tipiracil hydrochloride mixt	Lonsurf	Taiho Pharmaceutical	NME
2014/3/24	D10218	L02BB04	4291	Enzalutamide	Xtandi	Astellas Pharma	NME
2014/3/24	D10113	J05AX12	6250	Dolutegravir sodium	Tivicay	Viiv Healthcare	NME
2014/3/24	D10215		6313	Adsorbed influenza virus vaccine (H5N1)	Cell Culture-derived Influenza Emulsion HA Vaccine H5N1 for Intramuscular Injection	Chemo-Sero-Therapeutic Research Institute
2014/3/24	D10215		6313	Adsorbed influenza virus vaccine (H5N1)	Cell Culture-derived Influenza Vaccine H5N1	Kitasato Institute, Daiichi Sankyo
2014/1/17	D09993	B03AB06	2190	Ferric citrate hydrate	Riona	Japan Tobacco	NME
2014/1/17	D03730	V03AF02	3929	Dexrazoxane	Savene	Kissei Pharmaceutical
2014/1/17	D09572	C02KX05	2190	Riociguat	Adempas	Bayer Yakuhin	NME
2014/1/17	D10200		3969	Ipragliflozin L-proline	Suglat	Astellas Pharma	NME
2014/1/17	D07523	A16AA06	3999	Betaine	Cystadane	ReqMed	NME
2014/1/17	D09733	L01XE13	4291	Afatinib dimaleate	Giotrif	Boehringer Ingelheim	NME
2014/1/17	D09587	L01XC12	4291	Brentuximab vedotin	ADCetris	Takeda Pharmaceutical	BLA
2014/1/17	D10227		6343	Turoctocog alfa	NovoEight	Novo Nordisk Pharma
2013/9/27	D10469	J05AE14	6250	Simeprevir sodium	Sovriad	Janssen Pharmaceutical
2013/9/27	D08779		6343	pH4 Treated human normal immunoglobulin	Hizentra	CSL Behring
2013/9/20	D09208		3999	Cetilistat	Oblean	Takeda Pharmaceutical
2013/9/20	D05340	N05AX13	1179	Paliperidone palmitate	Xeplion	Janssen Pharmaceutical
2013/9/20	D09674	N07XX08	1290	Tafamidis meglumine	Vyndaqel	Pfizer
2013/9/20	D10501	R03AK10	2290	Fluticasone furoate - vilanterol trifenatate mixt	Relvar	GlaxoSmithKline	NME
2013/9/20	D10014	V09AB03	4300	Ioflupane I 123	Datscan	Nihon Medi-Physics	NME
2013/9/20	D01084		4299	Talc	Unitalc	Nobelpharma
2013/9/20	D09980	L01XC14	6399	Trastuzumab emtansine	Kadcyla	Chugai Pharmaceutical	BLA
2013/6/28	D02342	C07AB07	2149	Bisoprolol	Bisono	Toa Eiyo	NME
2013/6/28	D09786		3949	Topiroxostat	Uriadec, Topiloric	Sanwa Kagaku Kenkyusho, Fujiyakuhin	NME
2013/6/28	D09729	A10BX10	2499	Lixisenatide	Lyxumia	Sanofi	NME
2013/6/28	D04486	M05BA06	3999	Ibandronate sodium	Bonviva	Chugai Pharmaceutical	NME
2013/6/28	D05446	L01XC13	4291	Pertuzumab	Perjeta	Chugai Pharmaceutical	BLA
2013/6/18	D10455	J07AL02	6311	Pneumococcal 13-valent conjugate vaccine	Prevenar	Pfizer
2013/6/18	D10215		6313	Adsorbed influenza virus vaccine (H5N1)	Cell Culture-derived Influenza Vaccine H5N1	Takeda Pharmaceutical, Baxter
2013/4/26				Adsorbed influenza virus vaccine (prototype)	Cell Culture-derived Influenza Vaccine	Takeda Pharmaceutical, Baxter
2013/3/25	D08838		2399	Acotiamide hydrochloride	Acofide	Zeria Pharmaceutical	NME
2013/3/25	D04641		1169	Istradefylline	Nouriast	Kyowa Hakko Kirin	NME
2013/3/25	D02780	N07BB03	1190	Acamprosate calcium	Regtect	Nippon Shinyaku	NME
2013/3/25	D05775	N03AF03	1139	Rufinamide	Inovelon	Eisai
2013/3/25	D03335	B05AA07	3319	Hetastarch	Voluven	Fresenius Kabi Japan
2013/3/25	D09783	L04AA29	3999	Tofacitinib citrate	Xeljanz	Pfizer	NME
2013/3/25	D09753	A10BH03	3969	Saxagliptin hydrate	Onglyza	Otsuka Pharmaceutical
2013/3/25	D05014		2499	Metreleptin	Metreleptin	Shionogi	BLA
2013/3/25	D02908	L01XD04	7290	Aminolevulinic acid hydrochloride	Alabel, Alaglio	Nobelpharma, SBI Pharmaceuticals	NME
2013/3/25	D09314	L01XC10	4291	Ofatumumab	Arzerra	GlaxoSmithKline	BLA
2013/3/25	D03546	L01BB06	4229	Clofarabine	Evoltra	Genzyme Japan	NME
2013/3/25	D10137	L01XE21	4291	Regorafenib hydrate	Stivarga	Bayer Yakuhin	NME
2013/3/25	D10756	J05AR09	6250	Elvitegravir - cobicistat - emtricitabine - tenofovir disoproxil mixt	Stribild	Japan Tobacco	NME
2013/3/25	D10215		6313	Adsorbed influenza virus vaccine (H5N1)	Adsorbed Influenza Vaccine H5N1	Denka Seiken
2013/3/25	D10003		6349	Hemin	Normosang	CMIC Holdings
2012/12/25	D03213	B01AF02	3339	Apixaban	Eliquis	Bristol-Myers	NME
2012/12/25	D05768	N04BC09	1169	Rotigotine	Neupro	Otsuka Pharmaceutical	NME
2012/12/25	D08575	N07XX06	1190	Tetrabenazine	Choreazine	Alfresa Pharma	NME
2012/12/25	D02472	P01BB51	6419	Atovaquone - proguanil hydrochloride mixt	Malarone	GlaxoSmithKline
2012/12/25	D00868	A07AA06	6419	Paromomycin sulfate	Ameparomo	Pfizer
2012/12/25	D08923	G04BD11	2590	Fesoterodine fumarate	Toviaz	Pfizer
2012/12/25	D03441	L04AB05	3999	Certolizumab pegol	Cimzia	UCB Japan	BLA
2012/12/25	D02176	A16AA01	3999	Levocarnitine	L-Cartin	Otsuka Pharmaceutical	NME
2012/9/28	D05255		2189	Omega-3-acid ethyl esters	Lotriga	Takeda Pharmaceutical	NME
2012/9/28	D05928	N03AX17	1139	Stiripentol	Diacomit	Meiji Seika Pharma
2012/9/28	D09574	S01LA05	1319	Aflibercept	Eylea	Bayer Yakuhin	BLA
2012/9/28	D02102	N07BC02	8219	Methadone hydrochloride	Methapain	Teikoku Seiyaku
2012/9/28	D01079	J01AA12	6129	Tigecycline	Tygacil	Pfizer	NME
2012/9/28	D00540	A03AB02 R03BB06	2259	Glycopyrrolate	Seebri	Novartis Pharma
2012/9/28	D09780		3969	Anagliptin	Suiny, Beskoa	Sanwa Kagaku Kenkyusho, Kowa	NME
2012/9/28	D09727	A10AE06	2492	Insulin degludec	Tresiba	Novo Nordisk Pharma	NME
2012/9/28	D05868	A16AX03	3999	Sodium phenylbutyrate	Buphenyl	CMIC Holdings, OrphanPacific
2012/9/28	D00254	L01AD01	4219	Carmustine	Gliadel	Nobelpharma
2012/9/28	D05380	L01XE11	4291	Pazopanib hydrochloride	Votrient	GlaxoSmithKline	NME
2012/7/27	D10214		6361	Adsorbed diphtheria-purified pertussis-tetanus-inactivated polio combined vaccine	Tetrabik	BIKEN
2012/7/27	D10214		6361	Adsorbed diphtheria-purified pertussis-tetanus-inactivated polio combined vaccine	Quattrovac	Chemo-Sero-Therapeutic Research Institute
2012/6/29	D04790	A06AX03	2359	Lubiprostone	Amitiza	Sucampo Pharma	NME
2012/6/29	D01146		3999	Iguratimod	Kolbet, Careram	Toyama Chemical, Eisai	NME
2012/6/29	D09756		3969	Teneligliptin hydrobromide hydrate	Tenelia	Mitsubishi Tanabe Pharm	NME
2012/6/29	D04666	H01CB03	2499	Lanreotide acetate	Somatuline	Teijin Pharma	NME
2012/6/29	D09400	L02BX02	2499	Degarelix acetate	Gonax	Astellas Pharma
2012/6/29	D03218	L01XE17	4291	Axitinib	Inlyta	Pfizer	NME
2012/5/18	D09958	J05AG05	6250	Rilpivirine hydrochloride	Edurant	Janssen Pharmaceutical	NME
2012/4/27	D05543		6313	Poliovirus vaccine inactivated	Imovax	Sanofi Pasteur
2012/3/30	D09586		2190	Bixalomer	Kiklin	Astellas Pharma
2012/3/30	D02004	N04BC07	1169	Apomorphine hydrochloride	Apokyn	Kyowa Hakko Kirin	NME
2012/3/30	D03896	R05CB13	2290	Dornase alfa	Pulmozyme	Chugai Pharmaceutical
2012/3/30	D05032	A16AX06	3999	Miglustat	Brazaves	Actelion Pharmaceuticals Japan	NME
2012/3/30	D09761		4291	Mogamulizumab	Poteligeo	Kyowa Hakko Kirin	BLA
2012/3/30	D09731	L01XE16	4291	Crizotinib	Xalkori	Pfizer	NME
2012/1/18	D08864		2149	Azilsartan	Azilva	Takeda Pharmaceutical	NME
2012/1/18	D07086	B01AF01	3339	Rivaroxaban	Xarelto	Bayer Yakuhin	NME
2012/1/18	D02624	N05CF04	1129	Eszopiclone	Lunesta	Eisai	NME
2012/1/18	D09539		1190	Gabapentin enacarbil	Regnite	Astellas Pharma	NME
2012/1/18	D02076	D11AX21 S01EA05	1319	Brimonidine tartrate	Aiphagan	Senju Pharmaceutical
2012/1/18	D02740	N01BB52 N01BB54	1219	Lidocaine - prilocaine mixt	Emla	Sato Pharmaceutical
2012/1/18	D00236	P01AX06	6290	Atovaquone	Samtirel	GlaxoSmithKline
2012/1/18	D02501	J02AX04	6179	Caspofungin acetate	Cancidas	MSD	NME
2012/1/18	D03684	M05BX04	3999	Denosumab	Ranmark	Daiichi Sankyo	BLA
2012/1/18	D10211	J07BH02	6313	Rotavirus vaccine, live, oral, pentavalent	RotaTeq	MSD
2011/9/26	D06597	A04AD12	2391	Fosaprepitant dimeglumine	Proemend	Ono Pharmaceutical	NME
2011/9/26	D04187	L04AA27	3999	Fingolimod hydrochloride	Imusera, Gilenya	Mitsubishi Tanabe Pharm, Novartis Pharma	NME
2011/9/26	D09012	J05AE11	6250	Telaprevir	Telavic	Mitsubishi Tanabe Pharm	NME
2011/9/26	D09315	L04AC08	3999	Canakinumab	Ilaris	Novartis Pharma	BLA
2011/9/26	D01161	L02BA03	4291	Fulvestrant	Faslodex	AstraZeneca	NME
2011/7/1	D01984	A02BC05	2329	Esomeprazole magnesium	Nexium	AstraZeneca
2011/7/1	D05419		3929	Pentetate calcium trisodium	Ditripentat-Cal	Nihon Medi-Physics	NME
2011/7/1	D09762		3929	Pentetate zinc trisodium	Zinc-Tripentat	Nihon Medi-Physics	NME
2011/7/1	D07595	N03AB05	1132	Fosphenytoin sodium hydrate	Fostoin	Nobelpharma
2011/7/1	D01080	J01XX09	6119	Daptomycin	Cubicin	MSD	NME
2011/7/1	D09535	G04BD12	2590	Mirabegron	Betanis	Astellas Pharma	NME
2011/7/1	D04358	L04AB06	3999	Golimumab	Simponi	Janssen Pharmaceutical	BLA
2011/7/1	D09319	R03AC18	2259	Indacaterol maleate	Onbrez	Novartis Pharma	NME
2011/7/1	D09566	A10BH05	3969	Linagliptin	Trazenta	Boehringer Ingelheim	NME
2011/7/1	D06320	L01XX38	4291	Vorinostat	Zolinza	MSD	NME
2011/7/1	D10193	J07BH01	6313	Live attenuated human rota virus vaccine, oral	Rotarix	GlaxoSmithKline
2011/7/1	D10192	J07BM01	6313	Recombinant adsorbed quadrivalent human papillomavirus virus-like particle vaccine	Gardasil	MSD
2011/4/22	D05349		2331	Pancrelipase	LipaCreon	Abbott Japan
2011/4/22	D09998	B03XA01	3999	Epoetin beta pegol	Mircera	Chugai Pharmaceutical	BLA
2011/4/22	D03822	N06DA03	1190	Rivastigmine	Exelon	Novartis Pharma, Ono Pharmaceutical
2011/4/22	D09546		3339	Edoxaban tosilate hydrate	Lixiana	Daiichi Sankyo	NME
2011/4/22	D02567	N06AB10	1179	Escitalopram oxalate	Lexapro	Mochida Pharmaceutical
2011/4/22	D00546	N01AB07	1119	Desflurane	Suprane	Baxter
2011/4/22	D08914	L01XX41	4291	Eribulin mesylate	Halaven	Eisai	NME
2011/2/23	D07132	N02AE01 N07BC01	1149	Buprenorphine	Norspan	Mundipharma
2011/1/21	D03021	L01BC07	4291	Azacitidine	Vidaza	Nippon Shinyaku	NME
2011/1/21	D04905	N06DX01	1190	Memantine hydrochloride	Memary	Daiichi Sankyo	NME
2011/1/21	D02173	N06DA04	1190	Galantamine hydrobromide	Reminyl	Janssen Pharmaceutical	NME
2011/1/21	D07082	B01AE07	3339	Dabigatran etexilate mesylate	Prazaxa	Boehringer Ingelheim	NME
2011/1/21	D08990	B02BX04	3999	Romiplostim	Romiplate	Kyowa Hakko Kirin	BLA
2011/1/21	D02735	M03AX01	1229	Rimabotulinumtoxin B	NerBloc	Eisai
2011/1/21	D09214	L04AC05	3999	Ustekinumab	Stelara	Janssen Pharmaceutical	BLA
2011/1/21	D00594	A10BX02	3969	Repaglinide	Surepost	Sumitomo Dainippon Pharma	NME
2011/1/21	D01206	M04AA03	3949	Febuxostat	Feburic	Teijin Pharma	NME
2011/1/21	D07578		3112	Eldecalcitol	Edirol	Chugai Pharmaceutical	NME
2011/1/17	D05313	J07BA02	6313	Japanese encephalitis vaccine	Encevac	Chemo-Sero-Therapeutic Research Institute
2011/1/14	D08804		6369	Freeze-dried live attenuated measles-rubella combined vaccine	Freeze-dried Live Attenuated Measles, Rubella Combined Vaccine "Hokken"	Kitasato Institute
2010/10/27	D10215		6313	Adsorbed influenza virus vaccine (H5N1)	Adsorbed Pandemic Influenza Vaccine (H5N1) "Kaketsuken"	Chemo-Sero-Therapeutic Research Institute
2010/10/27	D07085	L01AA09	4219	Bendamustine hydrochloride	Treakisym	SymBio Pharmaceuticals	NME
2010/10/27	D09736		3929	Iron (III) hexacyanoferrate (II)	Radiogardase	Nihon Medi-Physics
2010/10/27	D01213	C03XA01	2139	Tolvaptan	Samsca	Otsuka Pharmaceutical	NME
2010/10/27	D03978	B02BX05	3999	Eltrombopag olamine	Revolade	GlaxoSmithKline	NME
2010/10/27	D05339	N05AX13	1179	Paliperidone	Invega	Janssen Pharmaceutical	NME
2010/10/27	D05143	S01BC10	1319	Nepafenac	Nevanac	Alcon Japan	NME
2010/10/27	D08118	R06AE09	4490	Levocetirizine hydrochloride	Xyzal	GlaxoSmithKline
2010/10/27	D04121	A10BX04	2499	Exenatide	Byetta	Eli Lilly Japan	NME
2010/9/10	D09547		6250	Laninamivir octanoate hydrate	Inavir	Daiichi Sankyo	NME
2010/7/23	D06068	L01XE09	4291	Temsirolimus	Torisel	Pfizer	NME
2010/7/23	D07077	C02KX02	2190	Ambrisentan	Volibris	GlaxoSmithKline	NME
2010/7/23	D00709	N03AX14	1139	Levetiracetam	E Keppra	UCB Japan	NME
2010/7/23	D09741	G03FA17	2482	Drospirenone - ethinylestradiol betadex mixt	Yaz	Bayer Yakuhin	NME
2010/7/23	D03203	L04AA24	3999	Abatacept	Orencia	Bristol-Myers	BLA
2010/7/23	D10573		3999	Sodium hyaluronate crosslinked polymer	Synvisc	Genzyme Japan
2010/7/23	D06078	H05AA02	2439	Teriparatide	Forteo	Eli Lilly Japan
2010/7/23	D03062	G03XC02	3999	Bazedoxifene acetate	Viviant	Pfizer
2010/6/25	D09813	L04AX04	4291	Lenalidomide hydrate	Revlimid	Celgene
2010/4/16	D05350	L01XC08	4291	Panitumumab	Vectibix	Takeda Pharmaceutical, Takeda Bio Development Center	BLA
2010/4/16	D03940	L04AA25	6399	Eculizumab	Soliris	Alexion Pharma	BLA
2010/4/16	D02689	N05CH02	1190	Ramelteon	Rozerem	Takeda Pharmaceutical	NME
2010/4/16	D02716	N03AX16	1190	Pregabalin	Lyrica	Pfizer	NME
2010/4/16	D03864		1319	Diquafosol tetrasodium	Diquas	Santen Pharmaceutical
2010/4/16	D06553	A10BH04	3969	Alogliptin benzoate	Nesina	Takeda Pharmaceutical	NME
2010/1/20	D05343	A04AA05	2391	Palonosetron hydrochloride	Aloxi	Taiho Pharmaceutical	NME
2010/1/20	D01179	N06AX21	1179	Duloxetine hydrochloride	Cymbalta	Shionogi	NME
2010/1/20	D05940	V03AB35	3929	Sugammadex sodium	Bridion	Schering-Plough	NME
2010/1/20	D07080	A10BH02	3969	Vildagliptin	Equa	Novartis Pharma
2010/1/20	D06404	A10BX07	2499	Liraglutide	Victoza	Novo Nordisk Pharma
2010/1/20				Inactivated split-virus influenza A	Arepanrix	GlaxoSmithKline
2010/1/20	D09725	J07BB02	6313	Emulsified influenza HA vaccine (A/H1N1)	Arepanrix (withdrawn)	GlaxoSmithKline
2010/1/20	D09725	J07BB02	6313	Emulsified influenza HA vaccine (A/H1N1)	Cell-culture Derived Influenza A (H1N1) Emulsion HA Vaccine "Novartis" for Intramuscular Injection (withdrawn)	Novartis Pharma
2010/1/13	D03829		6250	Peramivir	Rapiacta	Shionogi	NME
2009/10/16	D02968	A04AD12	2391	Aprepitant	Emend	Ono Pharmaceutical	NME
2009/10/16	D07073	R01AD03	1329	Dexamethasone cipecilate	Erizas	Nippon Shinyaku	NME
2009/10/16	D06645	A10BH01	3969	Sitagliptin phosphate	Januvia	Banyu Pharmaceutical	NME
2009/10/16	D05201	B02BD09	6343	Nonacog alfa	BeneFIX	Wyeth
2009/10/16	D06294		4291	Miriplatin hydrate	Miripla	Sumitomo Dainippon Pharma	NME
2009/10/16	D05704	V03AF07	3959	Rasburicase	Rasuritek	Sanofi-Aventis
2009/10/16	D10212	J07BM02	6313	Recombinant adsorbed bivalent human papillomavirus-like particle vaccine (derived from Trichoplusia ni cells)	Cervarix	GlaxoSmithKline
2009/10/16	D10213	J07AL02	6311	Pneumococcal polysaccharide conjugate vaccine (adsorbed)	Prevenar	Wyeth
2009/7/7	D06412	C09XA02	2149	Aliskiren fumarate	Rasilez	Novartis Pharma	NME
2009/7/7	D00563	N06AX11	1179	Mirtazapine	Remeron, Reflex	Schering-Plough, Meiji Seika
2009/7/7	D02724	S01EE03	1319	Bimatoprost	Lumigan	Senju Pharmaceutical	NME
2009/7/7	D03820	G04CB02	2499	Dutasteride	Avolve	GlaxoSmithKline	NME
2009/4/22	D02574	N06BA09	1179	Atomoxetine hydrochloride	Strattera	Eli Lilly Japan	NME
2009/4/22	D00283	N05AH02	1179	Clozapine	Clozaril	Novartis Pharma
2009/4/22	D09598		6139	Tebipenem pivoxil	Orapenem	Meiji Seika
2009/4/22	D06315	D07AC17 R01AD12 R03BA05 R03BA09	1329	Fluticasone furoate	Allermist	GlaxoSmithKline
2009/4/22	D04540	A10AB06	2492	Insulin glulisine	Apidra	Sanofi-Aventis	NME
2009/4/22	D04024	L01XE07	4291	Lapatinib ditosylate	Tykerb	GlaxoSmithKline	NME
2009/2/23	D05313	J07BA02	6313	Japanese encephalitis vaccine	Jebik V	BIKEN
2009/1/21	D06405	V03AX02	1190	Nalfurafine hydrochloride	Remitch	Toray	NME
2009/1/21	D05697	S01LA04	1319	Ranibizumab	Lucentis	Novartis Pharma	BLA
2009/1/21	D05251	R03DX05	2290	Omalizumab	Xolair	Novartis Pharma
2009/1/21	D09198		3999	Minodronic acid hydrate	Recalbon, Bonoteo	Ono Pharmaceutical, Astellas Pharma	NME
2009/1/21	D06413	L01XE08	4291	Nilotinib hydrochloride hydrate	Tasigna	Novartis Pharma	NME
2009/1/21	D06414	L01XE06	4291	Dasatinib	Sprycel	Bristol-Myers	NME
2008/12/25	D04112	J05AG04	6250	Etravirine	Intelence	Janssen Pharmaceutical	NME
2008/12/25	D06670	J05AX09	6250	Maraviroc	Celsentri	Pfizer	NME
2008/10/16	D04667	V03AE03	2190	Lanthanum carbonate	Fosrenol	Bayer Yakuhin	NME
2008/10/16	D00354	N03AX09	1139	Lamotrigine	Lamictal	GlaxoSmithKline
2008/10/16	D06274	S01EE05	1319	Tafluprost	Tapros	Santen Pharmaceutical	NME
2008/10/16	D01583	L04AX05	3999	Pirfenidone	Pirespa	Shionogi	NME
2008/10/16	D00754	L04AX02	4291	Thalidomide	Thaled	Fujimoto Pharmaceutical
2008/10/16	D06120	H01AB01 V04CJ01	7990	Thyrotropin alfa	Thyrogen	Sato Pharmaceutical
2008/7/16	D01112	D10AD03	2699	Adapalene	Differin	Galderma
2008/7/16	D00074	R07AX01	2190	Nitric oxide	INOflo	INO Therapeutics LLC	NME
2008/7/16	D05386	S01LA03	1319	Pegaptanib sodium	Macugen	Pfizer	NME
2008/7/16	D00424	J04AB04	6169	Rifabutin	Mycobutin	Pfizer
2008/7/16	D04302	H01CC01	2499	Ganirelix acetate	Ganirest	Schering-Plough	NME
2008/7/16	D03325	D07AC13 D07XC03 R01AD09 R03BA07	1329	Mometasone furoate hydrate	Nasonex	Schering-Plough
2008/7/16	D03455	L01XC06	4291	Cetuximab	Erbitux	Merck	BLA
2008/7/16	D09190	L04AA04	6399	Anti-human thymocyte immunoglobulin, rabbit	Thymoglobuline	Sanofi-Aventis, Aventis Pharma
2008/6/24	D07133	J05AX08	6250	Raltegravir potassium	Isentress	Banyu Pharmaceutical	NME
2008/4/16	D03669	V03AC03	3929	Deferasirox	Exjade	Novartis Pharma	NME
2008/4/16	D00523	C09CA04	2149	Irbesartan	Irbetan, Avapro	Shionogi, Sumitomo Dainippon Pharma
2008/4/16	D01287	N01BB10	1214	Levobupivacaine hydrochloride	Popscaine	Maruishi Pharmaceutical
2008/4/16	D00317	J05AB09 S01AD07	6250	Famciclovir	Famvir	Asahi Kasei Pharma
2008/4/16	D02597	L04AB04	3999	Adalimumab	Humira	Abbott Japan
2008/4/16	D00294	C02DA01 V03AH01	3999	Diazoxide	Aroglycem	Schering-Plough
2008/4/16	D06402	L01XE04	4291	Sunitinib malate	Sutent	Pfizer	NME
2008/3/28	D06565	A16AB08	3959	Galsulfase	Naglazyme	AnGes MG	BLA
2008/1/25	D03674	B01AB05	3334	Enoxaparin sodium	Clexane	Sanofi-Aventis
2008/1/25	D00674	N02CC02	2160	Naratriptan hydrochloride	Amerge	GlaxoSmithKline
2008/1/25	D06410		3339	Thrombomodulin alfa	Recomodulin	Asahi Kasei Pharma	BLA
2008/1/25	D01176		1179	Blonanserin	Lonasen	Sumitomo Dainippon Pharma	NME
2008/1/25	D06282	N07BA03	7990	Varenicline tartrate	Champix	Pfizer	NME
2008/1/25	D02475	J01MA21	6241	Sitafloxacin	Gracevit	Daiichi Sankyo	NME
2008/1/25	D06408	A16AX05	3929	Zinc acetate	Nobelzin	Nobelpharma
2008/1/25	D06272	L01XE05	4291	Sorafenib tosylate	Nexavar	Bayer Yakuhin	NME
2008/1/25	D02994	L01XC02	4291	Rituximab	Rituxan	Bayer Yakuhin, Nihon Schering, Zenyaku Kogyo
2007/11/22	D06478	J05AE10	6250	Darunavir ethanolate	Prezista	Janssen Pharmaceutical	NME
2007/10/19	D03505	H05BX01	3999	Cinacalcet hydrochloride	Regpara	Kirin Pharma	NME
2007/10/19	D03799	G03DB08	2499	Dienogest	Dinagest	Mochida Pharmaceutical
2007/10/19	D04539	A10AE05	2492	Insulin detemir	Levemir	Novo Nordisk Pharma	NME
2007/10/19	D04288	V08CA10	7290	Gadoxetate disodium	EOB·Primovist	Bayer Yakuhin	NME
2007/10/19	D04023	L01XE03	4291	Erlotinib hydrochloride	Tarceva	Chugai Pharmaceutical	NME
2007/10/19	D05134	L01BB07	4229	Nelarabine	Arranon G	GlaxoSmithKline	NME
2007/10/19	D05424	B05AA01	6343	Human serum albumin	Medway, Stem	Mitsubishi Tanabe Pharm, Mitsubishi Pharma, Green Cross, Bipha
2007/10/19	D10215		6313	Adsorbed influenza virus vaccine (H5N1)	Adsorbed Pandemic Influenza Vaccine (H5N1) "Hokken"	Kitasato Institute
2007/10/19	D10215		6313	Adsorbed influenza virus vaccine (H5N1)	Adsorbed Pandemic Influenza Vaccine (H5N1) "Biken"	BIKEN
2007/10/4	D04499	A16AB09	3959	Idursulfase	Elaprase	Genzyme Japan	BLA
2007/7/31	D01115	C03DA04	2149	Eplerenone	Selara	Pfizer, Pharmacia	NME
2007/7/31	D00537	N03AX11	1139	Topiramate	Topina	Kyowa Hakko Kogyo
2007/7/31	D00765	M03AC09	1229	Rocuronium bromide	Eslax	Organon Japan
2007/7/31	D01964	S01EE04	1319	Travoprost	Travatanz	Alcon Japan	NME
2007/7/31	D02540	J01MA19	6241	Garenoxacin mesylate	Geninax	Toyama Chemical	NME
2007/7/31	D02500	D06BB10	6290	Imiquimod	Beselna	Mochida Pharmaceutical
2007/7/31	D02008	G04BE08	2590	Tadalafil	Cialis	Eli Lilly Japan	NME
2007/7/31	D02006	V10BX01	4300	Strontium chloride Sr 89	Metastron	GE Healthcare Limited, Amersham International PLC
2007/4/18	D03651	B03XA02	3999	Darbepoetin alfa	Nesp	Kirin Brewery
2007/4/18	D01844	B01AX05	3339	Fondaparinux sodium	Arixtra	GlaxoSmithKline	NME
2007/4/18	D01966	C10AX09	2189	Ezetimibe	Zetia	Schering-Plough	NME
2007/4/18	D06273		2590	Imidafenacin	Uritos, Staybla	Kyorin Pharmaceutical, Ono Pharmaceutical	NME
2007/4/18	D01703	R01AD13 R03BA08	2290	Ciclesonide	Alvesco	Teijin Pharma	NME
2007/4/18	D03207	A16AB07	3959	Alglucosidase alfa	Myozyme	Genzyme Japan	BLA
2007/4/18	D06409	L01XC07	4291	Bevacizumab	Avastin	Chugai Pharmaceutical	BLA
2007/1/26	D00423	J05AB04	6250	Ribavirin	Copegus	Chugai Pharmaceutical
2007/1/26	D02714	L01XE10	3999	Everolimus	Certican	Novartis Pharma	NME
2007/1/26	D00781	N04BX02	1169	Entacapone	Comtan	Novartis Pharma	NME
2007/1/26	D01832	N06BA07	1179	Modafinil	Modiodal	Alfresa Pharma
2007/1/26	D00567	L01XX33 M01AH01	1149	Celecoxib	Celecox	Pfizer, Pharmacia, Astellas Pharma, Yamanouchi Pharmaceutical
2007/1/26	D05394	H01AX01	2499	Pegvisomant	Somavert	Pfizer	NME
2007/1/26	D09189	J07AG51	6311	Haemophilus influenzae type b conjugate vaccine	ActHIB	Sanofi Pasteur
2007/1/4	D06503	L01BA04	4229	Pemetrexed sodium hydrate	Alimta, Randa, Briplatin, Platosin, Cisplatin	Eli Lilly Japan, Nihon Kayaku, Bristol, Pfizer, Maruko, Merck, Nichi-Iko
2006/10/20	D04670	A16AB05	3959	Laronidase	Aldurazyme	Genzyme Japan
2006/10/20	D00784	N04BC04	1169	Ropinirole hydrochloride	ReQuip	GlaxoSmithKline, SmithKline Beecham
2006/10/20	D01177	N01AH06	8219	Remifentanil hydrochloride	Ultiva	Janssen Pharmaceutical
2006/10/20	D02784	A16AB03	3959	Agalsidase alfa	Replagal	Sumitomo Dainippon Pharma, Sumitomo Pharmaceuticals
2006/10/20	D05440		7290	Perflubutane	Sonazoid	Daiichi Pharmaceutical
2006/10/20	D03150	L01XX32	4291	Bortezomib	Velcade	Janssen Pharmaceutical	NME
2006/10/20	D05409		6343	Rurioctocog alfa	Advate	Baxter
2006/10/20	D08776	J07AL01	6311	Pneumococcus vaccine	Pneumovax	Banyu Pharmaceutical
2006/7/26	D01855		2139	Mozavaptane hydrochloride	Physuline	Otsuka Pharmaceutical	NME
2006/7/26	D00332	N03AX12	1139	Gabapentin	Gabapen	Pfizer
2006/7/26	D04554	L03AB07	6399	Interferon beta-1a	Avonex	Genzyme Japan
2006/7/26	D00874	J01MA14 S01AE07	1319	Moxifloxacin hydrochloride	Vegamox	Alcon Japan	NME
2006/7/26	D04008	J05AF10	6250	Entecavir	Baraclude	Bristol	NME
2006/7/26	D06067	L01AX03	4219	Temozolomide	Temodal	Schering-Plough	NME
2006/4/20	D00825	N06AB06	1179	Sertraline hydrochloride	Jzoloft	Pfizer
2006/4/20	D01269	G04BD08	2590	Solifenacin succinate	Vesicare	Astellas Pharma, Yamanouchi Pharmaceutical	NME
2006/4/20	D01148	G04BD07	2590	Tolterodine tartrate	Detrusitol	Pfizer, Pharmacia
2006/4/20	D01685	H01CC02	2499	Cetrorelix acetate	Cetrotide	Shionogi, Nihon Kayaku
2006/1/23	D00769	B01AC04	3399	Clopidogrel bisulfate	Plavix	Sanofi Sante Lab, Daiichi Pharmaceutical
2006/1/23	D01164	N05AX12	1179	Aripiprazole	Abilify	Otsuka Pharmaceutical	NME
2006/1/23	D04429	G03GA05	2413	Follitropin alfa	Gonalef	Serono Japan
2006/1/23	D01965	G04CA04	2590	Silodosin	Urief, Silodosin	Kissei Pharmaceutical, Shiono Finesse	NME
2006/1/23	D00964	L02BG04	4291	Letrozole	Femara	Ciba-Geigy Japan
2005/10/11	D00321	D11AX10 G04CB01	2499	Finasteride	Propecia	Banyu Pharmaceutical
2005/10/11	D00625	A10BF02	3969	Miglitol	Seibule	Sanwa Kagaku Kenkyusho
2005/10/11	D00874	J01MA14 S01AE07	1319	Moxifloxacin hydrochloride	Avelox	Bayer Yakuhin	NME
2005/10/11	D00171		7225	Inulin	Inulead	Kanto Chemical, Fujiyakuhin	NME
2005/10/11	D08804		6369	Freeze-dried live attenuated measles-rubella combined vaccine	Freeze-Dried Live Attenuated Measles and Rubella Combined Vaccine "Takeda"	Takeda Pharmaceutical
2005/7/25	D01836	J01DH04	6139	Doripenem hydrate	Finibax	Shionogi	D03895
2005/7/25	D01843	V09IX04	4300	Fludeoxyglucose F 18	FDG scan	Nihon Medi-Physics, Medical & Pharmacological Research Center Foundation
2005/7/25	D03259	L01XC05	4239	Gemtuzumab ozogamicin	Mylotarg	Wyeth Lederle Japan, Wyeth
2005/7/25	D08804		6369	Freeze-dried live attenuated measles-rubella combined vaccine	Mearubik	BIKEN
2005/4/11	D02596	L04AC07	6399	Tocilizumab	Actemra	Chugai Pharmaceutical	BLA
2005/4/11	D01227	C02KX01	2190	Bosentan	Tracleer	Actelion Pharmaceuticals Japan	NME
2005/4/11	D01980		2655	Luliconazole	Lulicon	Nihon Nohyaku, Pola Chemical Industries	NME
2005/4/11	D00578	J02AC03	6179	Voriconazole	Vfend	Pfizer	NME
2005/4/11	D04430	G03GA06	2413	Follitropin beta	Follistim	Organon Japan
2005/4/11	D00045	C01EB10	7990	Adenosine	Adenoscan	Suntory, Daiichi Suntory Pharma
2005/4/11	D01418		4291	Tamibarotene	Amnolake	Toko Pharmaceutical Industrial	NME
2005/3/23	D01199	J05AF09	6250	Emtricitabine	Emtriva	Japan Tobacco	NME
2005/3/23	D02297	J05AR03	6250	Emtricitabine - tenofovir disoproxil fumarate mixt	Truvada	Japan Tobacco
2005/3/18	D01790	L01XA03	4291	Oxaliplatin	Elplat	Yakult Honsha	NME
2005/1/19	D01915	C10AA07	2189	Rosuvastatin calcium	Crestor	AstraZeneca	NME
2005/1/19	D00742	L04AB01	3999	Etanercept	Enbrel	Wyeth Lederle Japan, Wyeth
2004/12/24	D02867	J05AE07	6250	Fosamprenavir calcium hydrate	Lexiva	GlaxoSmithKline
2004/11/5	D03256	J05AB14	6250	Valganciclovir hydrochloride	Valixa	Tanabe Seiyaku
2004/10/22	D01655	J05AF08	6250	Adefovir dipivoxil	Hepsera, Zefix	GlaxoSmithKline	NME
2004/10/22	D02748	L03AB10	6399	Peginterferon alfa-2b	Pegintron	Schering-Plough
2004/10/22	D01929	R03BB04	2259	Tiotropium bromide hydrate	Spiriva	Boehringer Ingelheim	NME
2004/10/22	D02040		7223	Pralmorelin dihydrochloride	GHRP	Kaken Pharmaceutical
2004/10/22	D01968	M05BA08	3999	Zoledronic acid	Zometa	Ciba-Geigy Japan	NME
2004/4/23	D03260	G04BE09	2590	Vardenafil hydrochloride hydrate	Levitra	Bayer Yakuhin	NME
2004/4/23	D02283		4300	Iomazenil (123I)	Benzodine	Nihon Medi-Physics
2004/3/25	D01982	J05AF07	6250	Tenofovir disoproxil fumarate	Viread	Japan Tobacco	NME
2004/1/29	D02217	G03XC01	3999	Raloxifene hydrochloride	Evista	Eli Lilly Japan
2004/1/29	D01204	C09CA08	2149	Olmesartan medoxomil	Olmetec	Sankyo	NME
2004/1/29	D03228	A16AB04	3959	Agalsidase beta	Fabrazyme	Genzyme Japan
2004/1/29	D01205	N05CM18	1129	Dexmedetomidine hydrochloride	Precedex	Abbott Japan, Maruishi Pharmaceutical	NME
2004/1/29	D01854	A10BX08	3969	Mitiglinide calcium hydrate	Glufast	Shiono Finesse, Kissei Pharmaceutical	NME
2004/1/29	D02632		2391	Indisetron hydrochloride	Sinseron	Nisshin Pharma, Nisshin Kyorin Pharmaceutical	NME
2003/12/18	D01276	J05AE08	6250	Atazanavir sulfate	Reyataz	Bristol	NME
2003/10/16	D01162	S01LA01	1319	Verteporfin	Visudyne	Ciba-Geigy Japan
2003/10/16	D02747	L03AB11	6399	Peginterferon alfa-2a	Pegasys	Chugai Pharmaceutical
2003/10/16	D01429	D01AC15 J02AC01	6290	Fosfluconazole	Prodif	Pfizer
2003/10/16	D03250	A10AE04	2492	Insulin glargine	Lantus	Aventis Pharma
2003/10/16	D01985		4299	Talaporfin sodium	Laserphyrin	Wako Pure Chemical Industries, Meiji Seika	NME
2003/10/16	D00559	N04BC05	1169	Pramipexole hydrochloride	Sifrol	Boehringer Ingelheim
2003/10/16	D01078	J01FA15	6149	Telithromycin	Ketek (withdrawn)	Aventis Pharma	NME
2003/7/17	D01862	C10AA08	2189	Pitavastatin calcium	Livalo	Nissan Chemical Industries, Kowa	NME
2003/7/17	D00675	N02CC04	2160	Rizatriptan benzoate	Maxalt	Kyorin Pharmaceutical
2003/4/16	D01223	L01BC06	4223	Capecitabine	Xeloda	Chugai Pharmaceutical
2003/4/16	D00749	L04AA13	3999	Leflunomide	Arava	Aventis Pharma
2003/1/31	D01145		2149	Azelnidipine	Calblock	Ube Industries, Sankyo	NME
2003/1/31	D01983	V03AE02	2190	Sevelamer hydrochloride	Renagel, Phosblock	Chugai Pharmaceutical, Kirin Brewery
2002/10/8	D00652	S01EC04	1319	Brinzolamide	Azopt	Alcon Japan
2002/10/8	D00804	D11AX22 P02CF01	6429	Ivermectin	Stromectol	Banyu Pharmaceutical
2002/10/8	D00627	C09CA07	2149	Telmisartan	Micardis	Boehringer Ingelheim
2002/10/8	D02465	J02AX05	6179	Micafungin sodium	Funguard	Fujisawa Pharmaceutical	NME
2002/10/8	D01144	J01MA17	6241	Prulifloxacin	Sword, Quisnon	Juzen Chemical, Nippon Shinyaku, Meiji Seika	NME
2002/10/8	D03928		7290	Ferucarbotran	Resovist	Nihon Schering
2002/10/8	D00644	C07AB09	2123	Esmolol hydrochloride	Brevibloc	Maruishi Pharmaceutical
2002/10/8	D06466	L03AX03	6391	Freeze-dried BCG vaccine	Immucyst	Nihon Kayaku
2002/7/5	D00963	L02BG06	4291	Exemestane	Aromasin	Pharmacia	NME
2002/7/5	D01977	L01XE02	4291	Gefitinib	Iressa	AstraZeneca	NME
2002/7/5	D00364	R06AX13	4490	Loratadine	Claritin	Schering-Plough
2002/7/5	D01847		2123	Landiolol hydrochloride	Onoact	Ono Pharmaceutical, Nagase ChemteX	NME
2002/4/11	D07100	L01DB10	4235	Amrubicin hydrochloride	Calsed	Sumitomo Chemical, Sumitomo Pharmaceuticals	NME
2002/4/11	D01918		3999	Sivelestat sodium	Elaspol	Ono Pharmaceutical, Shiono Finesse	NME
2002/4/11	D00589	J01MA16 S01AE06	1319	Gatifloxacin	Gatiflo	Kyorin Pharmaceutical	NME
2002/4/11	D00687	R03AC12	2259	Salmeterol xinafoate	Serevent	GlaxoSmithKline, Glaxo Japan
2002/4/11	D05382	J01MA18	6241	Pazufloxacin mesilate	PASIL, Pazucross	Toyama Chemical, Mitsubishi Pharma, Yoshitomi Pharmaceutical	NME
2002/4/11	D01973	N02CC06	2160	Eletriptan hydrobromide	Relpax	Pfizer	NME
2002/1/17	D02737	J06BB16	6250	Palivizumab	Synagis	Dainabot
2002/1/17	D03058	L04AC02	6399	Basiliximab	Simulect	Ciba-Geigy Japan
2002/1/17	D03234	M05BA07	3999	Sodium risedronate hydrate	Actonel, Benet	Ajinomoto, Takeda Pharmaceutical
2002/1/17	D02598	L04AB02	2399	Infliximab	Remicade	Tanabe Seiyaku
2002/1/17	D01370	L01BB04	4291	Cladribine	Leustatin	Janssen Pharmaceutical, Janssen Kyowa
2002/1/17	D00854	J01FG02	6119	Quinupristin - dalfopristin mixt	Synercid	Aventis Pharma	NME
2001/11/21	D01441	L01XE01	4291	Imatinib mesylate	Glivec	Ciba-Geigy Japan	NME
2001/11/21	D00423	J05AB04	6250	Ribavirin	Rebetol	Schering-Plough
2001/10/2	D02744	L03AB09 S01AD05	6399	Interferon alfacon-1	Advaferon (withdrawn), Infergen (withdrawn)	Yamanouchi Pharmaceutical, Amgen
2001/10/2	D04475	A10AB05 A10AD05	2492	Insulin aspart	NovoRapid	Novo Nordisk Pharma
2001/10/2	D01057	J01DH05	6139	Biapenem	Omegacin	Wyeth Lederle Japan, Hishiyama Pharmaceutical, Kanegafuchi Chemical Industry
2001/10/2	D03470		7321	Phtharal	Disopa	Johnson & Johnson
2001/10/2	D01845		2233	Fudosteine	Spelear, Cleanal, Fudosteine	Dojin Iyaku-Kako, Yuki Gosei Kogyo, SSP, Yoshitomi Pharmaceutical, Welfide Pharma, Mitsubishi Pharma	NME
2001/10/2	D03467		7321	Peracetic acid	Acecide	Saraya
2001/6/20	D02994	L01XC02	4291	Rituximab	Rituxan	Zenyaku Kogyo
2001/6/20	D04477	A10AB04 A10AC04 A10AD04	2492	Insulin lispro	Humalog	Eli Lilly Japan
2001/6/20	D00529	R03DC03	4490	Montelukast sodium	Singulair, Kipres	Banyu Pharmaceutical, Kyorin Pharmaceutical
2001/6/20	D00661	N07AX03	2399	Cevimeline hydrochloride	Evoxac, Saligren	Ishihara Sangyo, Snow Brand Milk Products, Nihon Kayaku	NME
2001/6/20	D00415	N02CC03	2160	Zolmitriptan	Zomig	AstraZeneca
2001/4/4	D03257	L01XC03	4291	Trastuzumab	Herceptin	Roche Japan
2001/4/4	D05261	A02BC01	2329	Omeprazole sodium injection	Omepral	AstraZeneca
2001/4/4	D00947	J01XX08	6249	Linezolid	Zyvox	Pharmacia
2001/4/4	D02505	J01CR05 J01RA01	6139	Tazobactam and piperacillin for injection	Tazocin, Penmode	Otsuka Chemical, Toyama Chemical, Taiho Pharmaceutical	NME
2001/4/4	D03362		2699	Trafermin	Fiblast	Kaken Pharmaceutical
2001/4/4	D01662		3112	Falecalcitriol	Hornel, Fulstan	Shiono Koryo, Sumitomo Pharmaceuticals, Taisho Pharmaceutical	NME
2001/4/4	D00831	P01BC02	6419	Mefloquine hydrochloride	Mephaquin	SSP, Dojin Iyaku-Kako
2001/4/4	D04048	N01BB09	1214	Ropivacaine hydrochloride	Anapeine	Astra Japan
2001/4/4	D01552		1190	Edaravone	Radicut	Mitsubishi-Tokyo Pharmaceuticals	NME
2000/12/22	D02372		1179	Perospirone hydrochloride hydrate	Lullan	Sumitomo Chemical, Sumitomo Pharmaceuticals	NME
2000/12/22	D01192	R01AC08 S01GX09	4490	Olopatadine hydrochloride	Allelock	Kyowa Hakko Kogyo, Kyowa Oil&Chemical	NME
2000/12/22	D00960	L02BG03	4291	Anastrozole	Arimidex	AstraZeneca
2000/12/22	D00411	R03DC01	4490	Zafirlukast	Accolate	AstraZeneca, Zeneca
2000/12/22	D00969	M01AC06	1149	Meloxicam	Mobic	Boehringer Ingelheim
2000/12/22	D01866	M01AC05	1149	Lornoxicam	Lorcam	Taisho Pharmaceutical
2000/12/22	D02168	L01XX17	4240	Topotecan hydrochloride	Hycamtin	GlaxoSmithKline, SmithKline Beecham
2000/12/22	D00454	N05AH03	1179	Olanzapine	Zyprexa	Eli Lilly Japan
2000/12/12	D00458	N05AH04	1179	Quetiapine fumarate	Seroquel	AstraZeneca, Zeneca
2000/12/12	D00900	J05AH02	6250	Oseltamivir phosphate	Tamiflu	Roche Japan	NME
2000/12/12	D02498	J05AR10	6250	Lopinavir mixture with ritonavir	Kaletra	Dainabot
2000/9/22	D03233		1319	Acitazanolast hydrate	Zepelin	Wakamoto	NME
2000/9/22	D01717	S01GX02	1319	Levocabastine hydrochloride	Livostin	Janssen Kyowa
2000/9/22	D00400	C09CA03	2149	Valsartan	Diovan	Ciba-Geigy Japan
2000/9/22	D00706	N05CF02	1129	Zolpidem tartrate	Myslee	Fujisawa Sanofi Sante Lab, Fujisawa Pharmaceutical
2000/9/22	D00671	R06AX26	4490	Fexofenadine hydrochloride	Allegra	Aventis Pharma, Hoechst Marion Roussel
2000/9/22	D02260	N06AB05	1179	Paroxetine hydrochloride hydrate	Paxil	SmithKline Beecham
2000/9/22	D08796	B01AD12	6343	Human activated protein C, freeze-dried concentrated	Anact	Chemo-Sero-Therapeutic Research Institute
2000/9/22	D00746	L03AB08	6399	Interferon beta-1b	Betaferon	Nihon Schering
2000/9/22	D00353	J05AF05	6250	Lamivudine	Zefix	Glaxo Japan
2000/9/22	D03355	V08CA02	7290	Meglumine gadoterate	Magnescope	Eiken Chemical	NME
2000/7/3	D01654		4490	Bepotastine besylate	Talion	Ube Industries, Tanabe Seiyaku	NME
2000/7/3	D01925		1190	Taltirelin hydrate	Ceredist	Tanabe Seiyaku	NME
2000/7/3	D03644	B01AB09	3339	Danaparoid sodium	Orgaran	Organon Japan
2000/7/3	D01025	S01ED03	1319	Levobunolol hydrochloride	Mirol	Kyorin Pharmaceutical
2000/7/3	D00398	J05AB11	6250	Valacyclovir hydrochloride	Valtrex	Wellcome Japan
2000/7/3	D01098		3112	Maxacalcitol	Oxarol	Chugai Pharmaceutical	NME
2000/7/3	D03306	A06AC08	2399	Calcium polycarbophil	Polyful, Colonel	Hokuriku Seiyaku, Fujisawa Pharmaceutical	NME
2000/7/3	D01474	V08AB09	7219	Iodixanol	Visipaque	Daiichi Pharmaceutical
2000/3/10	D01253	N05BA09	1139	Clobazam	Mystan	Dainippon Seiyaku	NME
2000/3/10	D01128		4490	Ramatroban	Baynas	Bayer Yakuhin
2000/3/10	D00172		6343	Eptacog alfa (activated)	NovoSeven	Novo Nordisk Pharma
2000/3/10	D02258	C10AA05	2189	Atorvastatin calcium hydrate	Lipitor	Warner Lambert
2000/3/10	D03163	S01BC11	1319	Bromfenac sodium	Bronuck	Senju Pharmaceutical
2000/3/10	D02134	J01FA10	6149	Azithromycin hydrate	Zithromac	Pfizer
2000/2/25	D00895	J05AG02	6250	Delavirdine mesylate	Rescriptor	Warner Lambert
2000/1/18	D00676	N02CC01	2160	Sumatriptan succinate	Imigran	Glaxo Wellcome
2000/1/18	D01131	A02BA08	2325	Lafutidine	Protecadin	Fujirebio, Taiho Pharmaceutical, Central Glass	NME
2000/1/18	D01450	N01BB01	1214	Bupivacaine hydrochloride	Marcain	Astra Japan
2000/1/18	D01550		2659	Liranaftate	Zefnart	Tosoh Akzo, Zenyaku Kogyo, Solvay Seiyaku	NME
2000/1/18	D01125	D05AX02	2691	Calcipotriene	Dovonex	Teikoku Seiyaku

New Drug Approvals in Japan

Drugs with new active ingredients