Antivirals Antivirals| Pathogen | Class | Generic name | ATC | KEGG | Products (USA) | Products (Japan) | Indications | |
| Herpes simplex virus (HSV) | DNA polymerase inhibitor | Purine analog | Acyclovir | J05AB01 D06BB03 S01AD03 | D00222 D02764 | ZOVIRAX ACYCLOVIR |
ZOVIRAX, ACTIOS | Herpes simplex virus infections in immunocompromised patients (H00365) Herpes genitalis (H00365) Herpes simplex encephalitis (H01417) Neonatal herpes simplex virus infection (H00365) Varicella-Zoster infections in immunocompromised patients (H00366) |
| Vidarabine | J05AB03 S01AD06 | D06298 | ARASENA | Herpes simplex encephalitis (H01417) Herpes zoster (H00366) Herpes simplex (H00365) |
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| Famciclovir | J05AB09 S01AD07 | D00317 | FAMVIR | FAMVIR | Herpes labialis [cold sores] (H00365) Genital herpes (H00365) Herpes zoster [shingles] (H00366) |
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| Valacyclovir | J05AB11 | D00398 D10518 | VALTREX | VALTREX | Cold Sores [Herpes Labialis] (H00365) Genital Herpes (H00365) Herpes Zoster (H00366) |
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| Penciclovir | J05AB13 D06BB06 | D05407 | DENAVIR | Recurrent herpes labialis [cold sores] (H00365) | ||||
| Pyrimidine analog | Trifluridine | S01AD02 | D00391 | VIROPTIC | Primary keratoconjunctivitis, recurrent epithelial keratitis (H00365) | |||
| Cytomegalovirus (CMV) | Purine analog | Ganciclovir | J05AB06 | D00333 D04301 | ZIRGAN CYTOVENE IV |
DENOSINE | Acute herpetic keratitis [dendritic ulcers] (H00365) CMV retinitis in immunocompromised patients (H00368) |
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| Valganciclovir | J05AB14 | D03256 | VALCYTE | VALIXA | Cytomegalovirus (CMV) retinitis, CMV Disease (H00368) | |||
| Nucleotide analog | Cidofovir | J05AB12 | D00273 | VISTIDE | CMV retinitis in patients with acquired immunodeficiency syndrome (AIDS) (H00368) | |||
| Phoshonate derivative | Foscarnet | J05AD01 | D00579 D02267 | FOSCAVIR | FOSCAVIR | CMV Retinitis in patients with acquired immunodeficiency syndrome [AIDS] (H00368) Acyclovir-resistant mucocutaneous HSV infections (H00366) |
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| Influenza virus | Uncoating inhibitor | Adamantane derivative | Rimantadine | J05AC02 | D00901 | FLUMADINE | Prophylaxis and treatment of illness caused by various strains of influenza A virus (H00398) | |
| Amantadine | D00777 | AMANTADINE HYDROCHLORIDE | SYMMETREL | Prophylaxis and treatment of illness caused by various strains of influenza A virus (H00398) | ||||
| Neuraminidase inhibitor | Zanamivir | J05AH01 | D00902 D01937 | RELENZA | RELENZA | Uncomplicated acute illness due to influenza A and B virus (H00398) | ||
| Oseltamivir | J05AH02 | D00900 | TAMIFLU | TAMIFLU | Uncomplicated acute illness due to influenza infection (H00398) | |||
| Peramivir | D03829 | RAPIVAB | RAPIACTA | Acute uncomplicated influenza (H00398) | ||||
| Laninamivir | D09547 | INAVIR | Treatment and prevention of influenza A and B virus (H00398) | |||||
| Hepatitis B virus (HBV) | Reverse transcriptase inhibitor | Nucleoside analog | Lamivudine | J05AF05 | D00353 | EPIVIR-HBV | ZEFIX | Chronic hepatitis B virus (HBV) infection (H00412) |
| Entecavir | J05AF10 | D04008 | BARACLUDE | BARACLUDE | Chronic hepatitis B virus infection (H00412) | |||
| Telbivudine | J05AF11 | D06675 | TYZEKA | Chronic hepatitis B in adult patients (H00412) | ||||
| Nucleotide analog | Tenofovir disoproxil | J05AF07 | D01982 | VIREAD | TENOZET | Chronic hepatitis B (H00412) HIV-1 infection (H00406) |
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| Adefovir dipivoxil | J05AF08 | D01655 | HEPSERA | HEPSERA | Chronic hepatitis B (H00412) | |||
| Invasion / integration inhibitor | Interferon | Interferon alfa | L03AB01 | D03305 | SUMIFERON | Improvement of viremia in chronic active hepatitis B (H00412) Improvement of viremia in chronic hepatitis C, compensated cirrhosis (H00413) Subacute sclerosing panencephalitis [combination with Inosine pranobex] (H00394 H01417) Antineoplastic |
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| Interferon beta | L03AB02 | D03304 | FERON | Improvement of viremia in chronic active hepatitis B (H00412) Improvement of viremia in chronic hepatitis C, compensated cirrhosis (H00413) Antineoplastic |
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| Interferon alfa-2b | L03AB05 | D02745 | INTRON A | INTRON A | Chronic hepatitis C (H00413) Chronic hepatitis B (H00412) Condylomata acuminata (H01418) AIDS-related kaposi's sarcoma (H00406) Hairy cell leukemia Malignant melanoma Follicular lymphoma |
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| Peginterferon alfa-2a | L03AB11 | D02747 | PEGASYS | PEGASYS | Chronic Hepatitis C (H00413) Chronic Hepatitis B (H00412) |
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| Hepatitis C virus (HCV) | DNA polymerase inhibitor | Nucleoside analog | Ribavirin | J05AB04 | D00423 | COPEGUS REBETOL |
COPEGUS REBETOL |
Chronic hepatitis C (CHC) virus infection [combination with PEGASYS] (H00413) Chronic Hepatitis C (CHC) [combination with INTRON A] (H00413) |
| Protease inhibitor | NS3/NS4A protease inhibitor | Telaprevir | J05AE11 | D09012 | TELAVIC | Chronic hepatitis C (CHC) virus infection (H00413) | ||
| Boceprevir | J05AE12 | D08876 | VICTRELIS | Chronic hepatitis C genotype 1 infection [combination with peginterferon alfa and ribavirin] (H00413) | ||||
| Simeprevir | J05AE14 | D10469 | OLYSIO | SOVRIAD | chronic hepatitis C (CHC) genotype 1 infection [combination with peginterferon alfa and ribavirin] (H00413) | |||
| Vaniprevir | D09987 | VANIHEP | Chronic hepatitis C (CHC) virus infection (H00413) | |||||
| NS3 protease inhibitor | Asunaprevir | J05AE15 | D10093 | SUNVEPRA | Chronic hepatitis C (CHC) virus infection (H00413) | |||
| Polymerase inhibitor | NS5A polymerase inhibitor | Daclatasvir | J05AX14 | D10105 | DAKLINZA | Chronic hepatitis C serogroup 1 infection (H00413) | ||
| NS5B polymerase inhibitor | Sofosbuvir | J05AX15 | D10366 | SOVALDI | SOVALDI | Chronic hepatitis C (CHC) genotype 1, 2, 3 or 4 infection (H00413) | ||
| Combination of polymerase inhibitor | Ledipasvir and sofosbuvir | D10578 | HARVONI | HARVONI | Chronic hepatitis C (CHC) genotype 1 infection (H00413) | |||
| Combination of polymerase inhibitor and protease inhibitor | Ombitasvir, paritaprevir and ritnavir | D10745 | TECHNIVIE | VIEKIRAX | Genotype 4 chronic hepatitis C virus (HCV) infection without cirrhosis (H00413) | |||
| Dasabuvir, ombitasvir, paritaprevir and ritnavir | D10582 | VIEKIRA PAK | Genotype 1 chronic hepatitis C virus (HCV) infection (H00413) | |||||
| Elbasvir - grazoprevir | D10778 | ZEPATIER | Genotypes 1 or 4 chronic hepatitis C virus (HCV) infection (H00413) | |||||
| Invasion / integration inhibitor | Interferon | Interferon alfa | L03AB01 | D03305 | SUMIFERON | Improvement of viremia in chronic active hepatitis B (H00412) Improvement of viremia in chronic hepatitis C, compensated cirrhosis (H00413) Subacute sclerosing panencephalitis [combination with Inosine pranobex] (H00394 H01417) Antineoplastic |
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| Interferon beta | L03AB02 | D03304 | FUERON | Improvement of viremia in chronic active hepatitis B (H00412) Improvement of viremia in chronic hepatitis C, compensated cirrhosis (H00413) Antineoplastic |
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| Interferon alfa-2b | L03AB05 | D02745 | INTRON A | INTRON | Chronic hepatitis C (H00413) Chronic hepatitis B (H00412) Condylomata acuminata (H01418) AIDS-related kaposi's sarcoma (H00406) Hairy cell leukemia Malignant melanoma Follicular lymphoma |
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| Peginterferon alfa-2b | L03AB10 | D02748 | PEGINTRON | PEGINTRON | Chronic Hepatitis C (CHC) (H00413) | |||
| Peginterferon alfa-2a | L03AB11 | D02747 | PEGASYS | PEGASYS | Chronic Hepatitis C (H00413) Chronic Hepatitis B (H00412) |
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| Human immunodeficiency virus (HIV) | Protease inhibitor | HIV protease inhibitor | Saquinavir | J05AE01 | D01160 | INVIRASE | INVIRASE | HIV-1 infection (H00406) |
| Indinavir | J05AE02 | D00897 D02861 | CRIXIVAN | CRIXIVAN | HIV infection (H00406) | |||
| Ritonavir | J05AE03 | D00427 | NORVIR | NORVIR | HIV-1 infection (H00406) | |||
| Nelfinavir | J05AE04 | D00899 | VIRACEPT | VIRACEPT | HIV-1 infection (H00406) | |||
| Fosamprenavir | J05AE07 | D03835 D02867 | LEXIVA | LEXIVA | human immunodeficiency virus (HIV-1) infection (H00406) | |||
| Atazanavir | J05AE08 | D01276 | REYATAZ | REYATAZ | HIV-1 infection (H00406) | |||
| Tipranavir | J05AE09 | D08605 | APTIVUS | HIV-1 infected patients who are treatment-experienced and infected with HIV-1 strains resistant to more than one protease inhibitor (co-administered with ritonavir) (H00406) | ||||
| Darunavir | J05AE10 | D06478 | PREZISTA | PREZISTA | human immunodeficiency virus (HIV-1) infection (H00406) | |||
| Combination of HIV protease inhibitors | Lopinavir and ritonavir | J05AR10 | D02498 | KALETRA | KALETRA | HIV-1 infection (H00406) | ||
| Reverse transcriptase inhibitor | Nucleoside analog | Zidovudine | J05AF01 | D00413 | RETROVIR | RETROVIR | HIV-1 infection (H00406) | |
| Didanosine | J05AF02 | D00296 | VIDEX EC | VIDEX EC | Human immunodeficiency virus (HIV)-1 infection (H00406) | |||
| Stavudine | J05AF04 | D00445 | ZERIT | ZERIT | Human immunodeficiency virus (HIV)-1 infection (H00406) | |||
| Lamivudine | J05AF05 | D00353 | EPIVIR | EPIVIR | Human immunodeficiency virus (HIV-1) infection (H00406) | |||
| Abacavir | J05AF06 | D00891 | ZIAGEN | ZIAGEN | HIV-1 infection (H00406) | |||
| Emtricitabine | J05AF09 | D01199 | EMTRIVA | EMTRIVA | HIV-1 infection (H00406) | |||
| Nucleotide analog | Tenofovir disoproxil | J05AF07 | D01982 | VIREAD | VIREAD | HIV-1 infection (H00406) Chronic hepatitis B (H00412) |
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| Tricyclic compounds | Nevirapine | J05AG01 | D00435 | VIRAMUNE | VIRAMUNE | HIV-1 infection (H00406) | ||
| Non-benzoxazinone derivatives | Delavirdine | J05AG02 | D00895 | RESCRIPTOR | HIV-1 infection (H00406) | |||
| Etravirine | J05AG04 | D04112 | INTELENCE | INTELENCE | Human immunodeficiency virus type 1 (HIV-1) infection (H00406) | |||
| Rilpivirine | J05AG05 | D09958 | EDURANT | EDURANT | Human immunodeficiency virus type 1 (HIV-1) infection (H00406) | |||
| Benzoxazinone derivatives | Efavirenz | J05AG03 | D00896 | SUSTIVA, ATRIPLA | STOCRIN | Human immunodeficiency virus type 1 (HIV-1) infection (H00406) | ||
| Combination of reverse transcriptase inhibitor | Zidovudine and lamivudine | J05AR01 | D07507 | COMBIVIR | COMBIVIR | HIV-1 infection (H00406) | ||
| Abacavir and lamivudine | J05AR02 | D08775 | EPZICOM | EPZICOM | HIV-1 infection (H00406) | |||
| Emtricitabine and tenofovir disoproxil | J05AR03 | D02297 | TRUVADA | TRUVADA | HIV-1 infection (H00406) | |||
| Emtricitabine, tenofovir disoproxil and rilpvirine | J05AR08 | D10571 | COMPLERA | COMPLERA | HIV-1 infection (H00406) | |||
| Invasion / integration inhibitor | HIV glycoprotein41 (gp41) inhibitor | Enfuvirtide | J05AX07 | D02499 | FUZEON | HIV-1 infection (H00406) | ||
| HIV integrase inhibitor | Raltegravir | J05AX08 | D07133 | ISENTRESS | ISENTRESS | Human immunodeficiency virus (HIV-1) infection (H00406) | ||
| Elvitegravir | J05AX11 | D06677 | VITEKTA | HIV-1 infection (H00406) | ||||
| Dolutegravir | J05AX12 | D10113 | TIVICAY | TIVICAY | Human immunodeficiency virus type 1 (HIV-1) infection (H00406) | |||
| Chemokine receptor 5 (CCR5) antagonist | Maraviroc | J05AX09 | D06670 | SELZENTRY | CELSENTRI | CCR5-tropic HIV-1 infection (H00406) | ||
| Interferon | Interferon alfa-2b | L03AB05 | D02745 | INTRON A | INTRON A | Chronic hepatitis C (H00413) Chronic hepatitis B (H00412) Condylomata acuminata (H01418) AIDS-related kaposi's sarcoma (H00406) Hairy cell leukemia Malignant melanoma Follicular lymphoma |
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| Combination | Combination of reverse transcriptase inhibitor and HIV integrase inhibitor | Emtricitabine, tenofovir disoproxil, elvitegravir and cobicistat | J05AR09 | D10756 | STRIBILD | STRIBILD | HIV-1 infection (H00406) | |
| Lamivudine, abacavir and dolutegravir | J05AR13 | D10600 | TRIUMEQ | TRIUMEQ | Human immunodeficiency virus type 1 (HIV-1) infection (H00406) | |||
| Emtricitabine, tenofovir alafenamide, elvitegravir and cobicistat | J05AR18 | D10755 | GENVOYA | GENVOYA | HIV-infection (H00406) | |||
| Other | Enhancement of other anti-HIV drug (CYP3A inhibitor) | Cobicistat | V03AX03 | D09881 | TYBOST | HIV-1 infection (H00406) | ||
| Respiratory syncytial virus (RSV) | DNA polymerase inhibitor | Nucleoside analog | Ribavirin | J05AB04 | D00423 | VIRAZOLE | Severe RSV lower respiratory tract infection (H00401) | |
| Growth inhibitor | Monoclonal antibody | Palivizumab | D02737 | SYNAGIS | SYNAGIS | RSV disease (H00401) | ||
| Measles virus | Immunoadjuvant | Nucleoside analog | Inosine pranobex | J05AX05 | D01995 | ISOPRINOSINE | Subacute sclerosing panencephalitis (H00394 H01417) | |
| Papillomavirus | Invasion / integration inhibitor | Interferon | Interferon alfa-2b | L03AB05 | D02745 | INTRON A | INTRON A | Chronic hepatitis C (H00413) Chronic hepatitis B (H00412) Condylomata acuminata (H01418) AIDS-related kaposi's sarcoma (H00406) Hairy cell leukemia Malignant melanoma Follicular lymphoma |
| Cytokine production promotor | Toll-like receptor agonist | Imiquimod | D06BB10 | D02500 | ALDARA, ZYCLARA | BESELNA | External genital warts (H01418) Actinic keratosis Superficial basal cell carcinoma |
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| Antioxidant | Flavonoid | Sinecatechins | D06BB12 | D08997 | VEREGEN | External genital and perianal warts (Condylomata acuminata) (H01418) | ||
| Category | Title |
| Disease pathway map | Herpes simplex infection |
| Influenza A | |
| Hepatitis B | |
| Hepatitis C | |
| Measles | |
| Drug structure map | Antivirals |
| Anti-HIV agents |