Antidiabetics Antidiabetics| Class | Generic name | ATC | KEGG | Product (USA) | Product (Japan) | ||
| Insulin and analogue (DG01636) |
Insulin analogue (DG01801) |
fast-acting (DG01796) |
Insulin lispro | A10AB04 A10AC04 A10AD04 |
D04477 | HUMALOG | HUMALOG |
| Insulin aspart | A10AB05 A10AD05 |
D04475 | NOVOLOG | NOBORAPID | |||
| Insulin glulisine | A10AB06 | D04540 | INSULIN GLULISINE | APIDRA | |||
| intermediate-acting | Insulin lispro | A10AB04 A10AC04 A10AD04 |
D04477 | HUMALOG | HUMALOG | ||
| long-acting (DG01797) |
Insulin glargine | A10AE04 | D03250 | LANTUS | INSULIN GLARGINE BS, LANTUS | ||
| Insulin detemir | A10AE05 | D04539 | LEVEMIR | LEVEMIR | |||
| Insulin degludec | A10AE06 | D09727 | TRESIBA | ||||
| Human insulin (DG01802) |
fast-acting (DG01798) |
Insulin human | A10AB01 A10AC01 A10AD01 A10AE01 A10AF01 |
D03230 | NOVOLIN70/30, HUMULIN | NOVOLIN, HUMULIN | |
| Insulin sensitizer (DG01685) |
Biguanide (DG01684) |
Metformin | A10BA02 | D00944 | GLUCOPHAGE, GLUMETZA | GLYCORAN, METGLUCO | |
| Buformin | A10BA02 | D02206 | DIBETOS | ||||
| Combination of biguanide | Metformin - glipizide | A10BD02 | D10265 | GLIPIZIDE AND METFORMIN HCL, GLIPIZIDE AND METFORMIN HYDROCHLORIDE | |||
| Metformin - glyburide | D10266 | GLUCOVANCE | |||||
| Metformin - rosiglitazone | A10BD03 | D10244 | AVANDAMET | ||||
| Metformin - pioglitazone | A10BD05 | D09744 | ACTOPLUS MET | METACT | |||
| Metformin - sitagliptin | A10BD07 | D10261 | JANUMET | ||||
| Metformin - saxagliptin | A10BD10 | D10263 | KOMBIGLYZE | ||||
| Metformin - linagliptin | A10BD11 | D10264 | JENTADUETO | ||||
| Metformin - alogliptin | A10BD13 | D10253 | KAZANO | ||||
| Metformin - repaglinide | A10BD14 | D10500 | PRANDIMET | ||||
| Metformin - dapagliflozin | A10BD15 | D10586 | XIGDUO | ||||
| Metformin - canagliflozin | A10BD16 | D10587 | INVOKAMET | ||||
| Thiazolidine (DG01683) |
Rosiglitazone | A10BG02 | D00596 | AVANDIA | |||
| Pioglitazone | A10BG03 | D00945 | ACTOS | ACTOS | |||
| Combination of thiazolidine | Rosiglitazone - metformin | A10BD03 | D10244 | AVANDAMET | |||
| Glimepiride - rosiglitazone | A10BD04 | D10251 | AVANDARYL | ||||
| Pioglitazone - metformin | A10BD05 | D09744 | ACTOPLUS MET | METACT | |||
| Pioglitazone - glimepiride | A10BD06 | D09848 | DUETACT | SONIAS | |||
| Pioglitazone - alogliptin | A10BD09 | D10159 | OSENI | LIOVEL | |||
| Insulin secretion promoter | DPP-4 inhibitor (DG01601) |
Sitagliptin | A10BH01 | D06645 | JANUVIA | GLACTIV, JANUVIA | |
| Vildagliptin | A10BH02 | D07080 | EQUA | ||||
| Saxagliptin | A10BH03 | D09753 | ONGLYZA | ||||
| D10262 | ONGLYZA | ||||||
| Alogliptin | A10BH04 | D06553 | NESINA | NESINA | |||
| Linagliptin | A10BH05 | D09566 | TRADJENTA | TRAZENTA | |||
| Teneligliptin | - | D09756 | TENELIA | ||||
| Anagliptin | - | D09780 | SUINY | ||||
| Trelagliptin | - | D10179 | ZAFATEC | ||||
| Combination of DPP-4 inhibitor | Alogliptin- pioglitazone | A10BD09 | D10159 | OSENI | LIOVEL | ||
| Sitagliptin - metformin | A10BD07 | D10261 | JANUMET | ||||
| Saxagliptin - metformin | A10BD10 | D10263 | KOMBIGLYZE | ||||
| Linagliptin - metformin | A10BD11 | D10264 | JENTADUETO | ||||
| Alogliptin - metformin | A10BD13 | D10253 | KAZANO | ||||
| Sulfonylurea (SU) (DG01734) |
first generation | Chlorpropamide | A10BB02 | D00271 | CHLORPROPAMIDE | ABEMIDE | |
| Tolbutamide | A10BB03 | D00380 | TOLBUTAMIDE | HOECHST RASTINON | |||
| Acetohexamide | A10BB31 | D00219 | DIMELIN | ||||
| Glyclopyramide | - | D01799 | DEAMELIN | ||||
| second generation | Glyburide | A10BB01 | D00336 | GLYNASE, DIABETA | EUGLUCON, DAONIL | ||
| Gliclazide | A10BB09 | D01599 | GLIMICRON | ||||
| third generation | Glimepiride | A10BB12 | D00593 | AMARYL | AMARYL | ||
| Tolazamide | A10BB05 | D00379 | TOLAZAMIDE | ||||
| Glipizide | A10BB07 | D00335 | GLIPIZIDE | ||||
| Combination of sulfonylurea (SU) | Glipizide - metformin | A10BD02 | D10265 | GLIPIZIDE AND METFORMIN HCL, GLIPIZIDE AND METFORMIN HYDROCHLORIDE | |||
| Glyburide - metformin | D10266 | GLUCOVANCE | |||||
| Glimepiride - rosiglitazone | A10BD04 | D10251 | AVANDARYL | ||||
| Pioglitazone - glimepiride | A10BD06 | D09848 | DUETACT | SONIAS | |||
| GLP-1 receptor agonist (DG01493) |
Exenatide | A10BX04 | D04121 | BYETTA, BYDUREON | BYETTA, BYDUREON | ||
| Liraglutide | A10BX07 | D06404 | SAXENDA, VICTOZA | ViCTOZA | |||
| Lixisenatide | A10BX10 | D09729 | LYXUMIA | ||||
| Albiglutide | A10BX13 | D08843 | TANZEUM | ||||
| Dulaglutide | - | D09889 | TRULICITY | TRULICITY | |||
| Postprandial hyperglycemia improving agent | Insulin secretion promoter, fast-acting | Glinide (DG01735) |
Repaglinide | A10BX02 | D00594 | PRANDIN | SUREPOST |
| Nateglinide | A10BX03 | D01111 | STARLIX | STARSIS, FASTIC | |||
| Mitiglinide | A10BX08 | D01854 | GLUFAST | ||||
| Combination of glinide | Metformin - repaglinide | A10BD14 | D10500 | PRANDIMET | |||
| Mitiglinide - voglibose | - | D10160 | GLUBES | ||||
| Polysaccharide-degrading enzyme inhibitor | Alpha-glucosidase inhibitor (DG01663)) |
Acarbose | A10BF01 | D00216 | PRECOSE | GLUCOBAY | |
| Miglitol | A10BF02 | D00625 | GLYSET | SEIBULE | |||
| Voglibose | A10BF03 | D01665 | BASEN | ||||
| Urine sugar eliminant | SGLT2 inhibitor (DG01794) |
Dapagliflozin | A10BX09 | D09763 | FARXIGA | FORXIGA | |
| Canagliflozin | A10BX11 | D09592 | INVOKANA | CANAGLU | |||
| Empagliflozin | A10BX12 | D10459 | JARDIANCE | JARDIANCE | |||
| Tofogliflozin | - | D09978 | APLEWAY, DEBERZA | ||||
| Luseogliflozin | - | D10195 | LUSEFI | ||||
| Ipragliflozin | - | D10200 | SUGLAT | ||||
| Combination of SGLT2 inhibitor | Dapagliflozin - metformin | A10BD15 | D10586 | XIGDUO | |||
| Canagliflozin - metformin mixt | A10BD16 | D10587 | INVOKAMET | ||||
| Category | Title |
| Disease pathway map | Type II diabetes |
| Type I diabetes | |
| Normal pathway map | Insulin signaling pathway |
| Insulin secretion | |
| Drug structure map | Antidiabetics |