Cardiovascular agents Cardiovascular agents| Class | Name | ATC | KEGG | Product (USA) | Product (Japan) | |
| Calcium channel blocker | Dihydropyridine (DG01928) | Amlodipine | C08CA01 | D00615 | NORVASC | AMLODIN, NORCASC |
| Felodipine | C08CA02 | D00319 | PLENDIL | SPLENDIL, MUNOBAL | ||
| Nicardipine | C08CA04 | D00617 | CARDENE | PERDIPINE | ||
| Nifedipine | C08CA05 | D00437 | ADALAT CC, PROCARDIA | ADARAT, EMABERIN, SEPAMIT | ||
| Nisoldipine | C08CA07 | D00618 | SULAR | BAYMYCARD | ||
| Nitrendipine | C08CA08 | D00629 | BAYLOTENSIN | |||
| Manidipine | C08CA11 | D01553 | CALSLOT | |||
| Barnidipine | C08CA12 | D01104 | HYPOCA | |||
| Azelnidipine | - | D01145 | CALBLOCK | |||
| Cilnidipine | - | D01173 | ATELEC | |||
| Aranidipine | - | D01562 | SAPRESTA, BEC | |||
| Efonidipine | - | D01604 | LANDEL | |||
| Nilvadipine | - | D01908 | NIVADIL | |||
| Benidipine | C08CA15 | D02045 | CONIEL | |||
| Benzodiazepine | Diltiazem | C05AE03 C08DB01 |
D00616 | CARDIZEM, DILACOR | HERBESSER | |
| Angiotensin II receptor antagonist (DG01495) |
Losartan | C09CA01 | D00357 | COZAAR | NU-LOTAN | |
| Eprosartan | C09CA02 | D02082 | TEVETEN | |||
| Valsartan | C09CA03 | D00400 | DIOVAN | DIOVAN | ||
| Irbesartan | C09CA04 | D00523 | AVAPRO | AVAPRO, IRBETAN | ||
| Candesartan cilexetil | C09CA06 | D00626 | ATACAND | CANDESARTAN, BLOPRESS | ||
| Telmisartan | C09CA07 | D00627 | MICARDIS | MICARDIS | ||
| Olmesartan medoxomil | C09CA08 | D01204 | BENICAR | OLMETEC | ||
| Azilsartan | - | D08864 | AZILVA | |||
| Azilsartan kamedoxomil | - | D08865 | EDARBI | |||
| ACE inhibitor (DG01501) |
Captopril | C09AA01 | D00251 | CAPTOPRIL | CAPTORIL | |
| Enalapril | C09AA02 | D00621 | VASOTEC | RENIVACE | ||
| Lisinopril | C09AA03 | D00362 | ZESTRIL | ZESTRIL, LONGES | ||
| Perindopril | C09AA04 | D00624 | ACEON | COVERSYL | ||
| Ramipril | C09AA05 | D00421 | ALTACE | |||
| Quinapril | C09AA06 | D00459 | ACCUPRIL | CONAN | ||
| Benazepril | C09AA07 | D00620 | LOTENSIN | CIBACEN | ||
| Cilazapril | C09AA08 | D01069 | INHIBACE | |||
| Trandolapril | C09AA10 | D00383 | MAVIK | ODRIC, PRERAN | ||
| Delapril | C09AA12 | D01667 | ADECUT | |||
| Moexipril | C09AA13 | D00623 | UNIVASC | |||
| Temocapril | C09AA14 | D01119 | ACECOL | |||
| Imidapril | C09AA16 | D01549 | TANATRIL | |||
| Alacepril | - | D01900 | CETAPRIL | |||
| Enalaprilat | - | D03769 | ENALAPRILAT | |||
| Renin inhibitor (DG01923) | Aliskiren | C09XA02 | D06412 | TEKTURNA | RASILEZ | |
| Diuretics | Thiazide (DG01749) | Hydrochlorothiazide | C03AA03 | D00340 | MICROZIDE | HYDROCHLOROTHIAZIDE |
| Trichlormethiazide | C03AA06 | D00658 | FLUITRAN | |||
| Benzylhydrochlorothiazide | - | D01246 | BEHYD | |||
| Thiazide analogs | Chlorthalidone | C03BA04 | D00272 | THALITONE | ||
| Mefruside | C03BA05 | D01877 | BAYCARON | |||
| Meticrane | C03BA09 | D01605 | ARRESTEN | |||
| Indapamide | C03BA11 | D00345 | INDAPAMIDE | TENAXIL, NATRIX | ||
| Tripamide | - | D01895 | NORMONAL | |||
| Loop (DG01748) | Furosemide | C03CA01 | D00331 | FUROSEMIDE | EUTENSIN, LASIX | |
| K-sparing (DG01885) | Spironolactone | C03DA01 | D00443 | ALDACTONE | ALDACTONE | |
| Eplerenone | C03DA04 | D01115 | INSPRA | SELARA | ||
| Triamterene | C03DB02 | D00386 | DYRENIUM | TRITEREN | ||
| beta-Adrenergic receptor antagonist | non-selective (DG01464) | Pindolol | C07AA03 | D00513 | PINDOLOL | CARVISKEN |
| Propranolol | C07AA05 | D00483 | INNOPRAN XL, INDERAL | INDERAL | ||
| Nadolol | C07AA12 | D00432 | CORGARD | NADIC | ||
| Carteolol | C07AA15 S01ED05 |
D00599 | CARTEOLOL HYDROCHLORIDE | MIKELAN | ||
| Penbutolol | C07AA23 | D00602 | LEVATOL | |||
| Carvedilol | C07AG02 | D03415 | COREG, COREGCR | |||
| Nipradilol | - | D01691 | NIPRANOL, HYPADIL | |||
| beta1-selective (DG01461) | Metoprolol | C07AB02 | D00601 | LOPRESSOR | SELOKEN, LOPRESOR | |
| Atenolol | C07AB03 | D00235 | TENORMIN | TENORMIN | ||
| Acebutolol | C07AB04 | D00597 | SECTRAL | ACETANOL | ||
| Betaxolol | C07AB05 S01ED02 |
D00598 | BETOPTIC S | KERLONG | ||
| Bevantolol | C07AB06 | D01369 | CALVAN | |||
| Bisoprolol | C07AB07 | D00634 | ZEBETA | MAINTATE | ||
| D02342 | BISONO | |||||
| Celiprolol | C07AB08 | D01741 | SELECTOL | |||
| Nebivolol | C07AB12 | D06622 | BYSTOLIC | |||
| alpha-Adrenergic receptor antagonist (DG01465) | Prazosin | C02CA01 | D00609 | MINIPRESS | MINIPRESS | |
| Doxazosin | C02CA04 | D00608 | CARDURA | CARDENALIN | ||
| Urapidil | C02CA06 | D01333 | EBRANTIL | |||
| Terazosin | G04CA03 | D00610 | TERAZOSIN | HYTRACIN, VASOMET | ||
| Bunazosin | - | D01887 | DETANTOL | |||
| alpha, beta-Adrenergic receptor antagonist | Labetalol | C07AG01 | D00600 | TRANDATE | TRANDATE | |
| Carvedilol | C07AG02 | D00255 | COREG | ARTIST | ||
| Amosulalol | - | D01469 | LOWGAN | |||
| Arotinolol | - | D01830 | AROTINOLOL HYDROCHLORIDE | |||
| Centrally acting sympatholytic agent (DG01738) | Reserpine | C02AA02 | D00197 | RESERPINE | APOPLON | |
| Methyldopa | C02AB01 | D00405 | METHYLDOPA | ALDOMET | ||
| Clonidine | C02AC01 N02CX02 S01EA04 |
D00604 | CATAPRES | CATAPRES | ||
| Guanabenz | - | D00605 | WYTENS | |||
| Vasodilators | Hydralazine | C02DB02 | D01302 | HYDRALAZINE | APRESOLINE | |
| Endothelin receptor antagonist (DG01502) | Bosentan | C02KX01 | D01227 | TRACLEER | TRACLEER | |
| Ambrisentan | C02KX02 | D07077 | LETAIRIS | VOLiBRIS | ||
| Prostaglandin I2 receptor agonist | Epoprostenol | B01AC09 | D01337 | VELETRI, FLOLAN | FLOLAN | |
| Beraprost | B01AC19 | D01551 | CARELOAD, DORNER | |||
| Other | Tocopherol | A11HA03 | D01530 | JUVELA N | ||
| Deslanoside | C01AA07 | D01240 | DIGILANOGEN | |||
| Nitroprusside | C02DD01 | D00614 | NITROPRESS | NITOPRO | ||
| Ergoloid mesylates | C04AE01 | D02268 | HYDERGINE | |||
| Combination | Calcium channel blocker - Angiotensin II receptor antagonist | Amlodipine - Valsartan | C09DB01 | D09745 | EXFORGE | EXFORGE |
| Amlodipine - Olmesartan medoxomil | C09DB02 | D10285 | AZOR | |||
| Amlodipine - Telmisartan | C09DB04 | D09743 | TWYNSTA | MICAMLO | ||
| Amlodipine - Irbesartan | C09DB05 | D10243 | AIMIX | |||
| Amlodipine - Candesartan cilexetil | C09DB07 | D07569 | UNISIA | |||
| Amlodipine - Valsartan - Hydrochlorothiazide | C09DX01 | D10286 | EXFORGE HCT | |||
| Amlodipine - Olmesartan medoxomil - Hydrochlorothiazide | C09DX03 | D10288 | TRIBENZOR | |||
| Azelnidipine - Olmesartan medoxomil | - | D09594 | REZALTAS | |||
| Amlodipine - Azilsartan | - | D10524 | ZACRAS | |||
| Cilnidipine - Alsartan | - | D10525 | ATEDIO | |||
| Angiotensin II receptor antagonist - Diuretics | Losartan - Hydrochlorothiazide | C09DA01 | D07895 | HYZAAR | PREMINENT | |
| Eprosartan - Hydrochlorothiazide | C09DA02 | D10283 | TEVETEN HCT | |||
| Valsartan - Hydrochlorothiazide | C09DA03 | D09197 | DIOVAN HCT | CO-DIO | ||
| Irbesartan - trichlormethiazide | C09DA04 | D10480 | IRTRA | |||
| Candesartan cilexetil - Hydrochlorothiazide | C09DA06 | D09196 | ATACAND HCT | ECARD | ||
| Telmisartan - Hydrochlorothiazide | C09DA07 | D09219 | MICARDIS HCT | MICOMBI | ||
| Olmesartan medoxomil - Hydrochlorothiazide | C09DA08 | D10284 | BENICAR HCT | |||
| Azilsartan medoxomil - Chlorthalidone | C09DA09 | D10589 | EDARBYCLOR | |||
| ACE inhibitor - Diuretics | Captopril - Hydrochlorothiazide | C09BA01 | D10276 | CAPTOPRIL AND HYDROCHLOROTHIAZIDE | ||
| Enalapril maleate - Hydrochlorothiazide | C09BA02 | D10277 | VASERETIC | |||
| Lisinopril - Hydrochlorothiazide | C09BA03 | D10268 | ZESTORETIC | |||
| Benazepril - Hydrochlorothiazide | C09BA07 | D10279 | LOTENSIN HCT | |||
| Fosinopril - Hydrochlorothiazide | C09BA09 | D10280 | FOSINOPRIL SODIUM AND HYDROCHLOROTHIAZIDE | |||
| Moexipril - Hydrochlorothiazide | C09BA13 | D10281 | UNIRETIC | |||
| ACE inhibitor - Antiarrhythmic | Trandolapril - Verapamil | C09BB10 | D10282 | TARKA | ||
| Renin inhibitor - Diuretics | Aliskiren - Hydrochlorothiazide | C09XA52 | D10289 | TEKTURNA HCT | ||
| Renin inhibitor - Calcium channel blocker | Aliskiren - Amlodipine | C09XA53 | D10290 | TEKAMLO | ||
| Renin inhibitor - Calcium channel blocker - Diuretics | Aliskiren - Amlodipine - Hydrochlorothiazide | C09XA54 | D10291 | AMTURNIDE | ||
| beta-Adrenergic receptor antagonist - Diuretics | Propranolol - Hydrochlorothiazide | C07BA05 | D10274 | PROPRANOLOL HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE | ||
| Nadolol - Bendroflumethiazide | C07BA12 | D10272 | CORZIDE | |||
| Metoprolol - Hydrochlorothiazide | C07BB02 | D10273 | DUTOPROL | |||
| Bisoprolol - Hydrochlorothiazide | C07BB07 | D10275 | ZIAC | |||
| Atenolol - Chlorthalidone | C07CB03 | D10592 | TENORETIC | |||
| Centrally acting sympatholytic agent - Diuretics | Benzylhydrochlorothiazide - Reserpine - Carbazochrome | C02AA52 C02LA51 |
D04266 | BEHYD-RA | ||
| Diuretics | Hydrochlorothiazide - Spironolactone | C03EA01 | D10270 | ALDACTAZIDE | ||
| Class | Name | ATC | KEGG | Product (USA) | Product (Japan) | |||
| Sicilian Gambit | Vaughan Wiliams | |||||||
| Ion channel | Na | Fast | Class Ib | Lidocaine | C01BB01 | D02086 | XYLOCAINE | OLIVES |
| Class Ib | Mexiletine | C01BB02 | D00639 | MEXILETINE HYDROCHLORIDE | MEXITIL | |||
| Class III | Amiodarone | C01BD01 | D00636 | NEXTERONE | ANCARON | |||
| Class II | Propranolol | C07AA05 | D00483 | INNOPRAN XL | INDERAL | |||
| Class IV | Verapamil | C08DA01 | D00619 | VERELAN PM | VASOLAN | |||
| - | Bepridil | C08EA02 | D00631 | BEPRICOR | ||||
| Med | Class Ia | Quinidine | C01BA01 | D00642 | QUINIDINE GLUCONATE | |||
| D02272 | QUINIDINE SULFATE | QUINIDINE SULFATE | ||||||
| Class Ia | Procainamide | C01BA02 | D00477 | AMISALIN | PROCAINAMIDE HYDROCHLORIDE | |||
| Class Ib | Aprindine | C01BB04 | D01326 | ASPENON | ||||
| Class Ic | Propafenone | C01BC03 | D00640 | RYTHMOL | PRONON | |||
| Slow | Class Ia | Disopyramide | C01BA03 | D00303 | RYTHMODAN | |||
| D00637 | NORPACE | RYTHMODAN | ||||||
| Class Ia | Cibenzoline | C01BG07 | D01455 | CIVENOL | ||||
| Class Ia | Pirmenol | - | D01785 | PIMENOL | ||||
| Class Ic | Flecainide | C01BC04 | D00638 | FLECAINIDE ACETATE | TAMBOCOR | |||
| Class Ic | Pilsicainide | - | D01554 | SUNRYTHM | ||||
| Ca2+ | Class Ib | Aprindine | C01BB04 | D01326 | ASPENON | |||
| Class Ia | Cibenzoline | C01BG07 | D01455 | CIVENOL | ||||
| - | Bepridil | C08EA02 | D00631 | BEPRICOR | ||||
| Class IV | Verapamil | C08DA01 | D00619 | VERELAN PM | VASOLAN | |||
| Class IV | Diltiazem | C05AE03 C08DB01 |
D00616 | DILACOR | HERBESSER | |||
| Class III | Amiodarone | C01BD01 | D00636 | NEXTERONE | ANCARON | |||
| K | Class Ia | Procainamide | C01BA02 | D00477 | AMISALIN | PROCAINAMIDE HYDROCHLORIDE | ||
| Class Ia | Disopyramide | C01BA03 | D00303 | RYTHMODAN | ||||
| D00637 | NORPACE | RYTHMODAN | ||||||
| Class Ia | Quinidine | C01BA01 | D00642 | QUINIDINE GLUCONATE | ||||
| D02272 | QUINIDINE SULFATE | QUINIDINE SULFATE | ||||||
| Class Ib | Aprindine | C01BB04 | D01326 | ASPENON | ||||
| Class Ia | Cibenzoline | C01BG07 | D01455 | CIVENOL | ||||
| Class Ia | Pirmenol | - | D01785 | PIMENOL | ||||
| Class Ic | Flecainide | C01BC04 | D00638 | FLECAINIDE ACETATE | TAMBOCOR | |||
| - | Bepridil | C08EA02 | D00631 | BEPRICOR | ||||
| Class II Class III |
Sotalol | C07AA07 | D01026 | SOTYLIZE | SOTACOR | |||
| Class III | Amiodarone | C01BD01 | D00636 | NEXTERONE | ANCARON | |||
| Class III | Nifekalant | - | D01856 | SHINBIT | ||||
| If | Class Ib | Aprindine | C01BB04 | D01326 | ASPENON | |||
| Receptor | α | Class Ia | Quinidine | C01BA01 | D00642 | QUINIDINE GLUCONATE | ||
| D02272 | QUINIDINE SULFATE | QUINIDINE SULFATE | ||||||
| Class IV | Verapamil | C08DA01 | D00619 | VERELAN PM | VASOLAN | |||
| Class III | Amiodarone | C01BD01 | D00636 | NEXTERONE | ANCARON | |||
| β | Class Ic | Propafenone | C01BC03 | D00640 | RYTHMOL | PRONON | ||
| Class II Class III |
Sotalol | C07AA07 | D01026 | SOTYLIZE | SOTACOR | |||
| Class III | Amiodarone | C01BD01 | D00636 | NEXTERONE | ANCARON | |||
| Class II | Propranolol | C07AA05 | D00483 | INNOPRAN XL | INDERAL | |||
| M２ | Class Ia | Disopyramide | C01BA03 | D00303 | RYTHMODAN | |||
| D00637 | NORPACE | RYTHMODAN | ||||||
| Class Ia | Quinidine | C01BA01 | D00642 | QUINIDINE GLUCONATE | ||||
| D02272 | QUINIDINE SULFATE | QUINIDINE SULFATE | ||||||
| Class Ia | Cibenzoline | C01BG07 | D01455 | CIVENOL | ||||
| Class Ia | Pirmenol | - | D01785 | PIMENOL | ||||
| - | Atropine | A03BA01 S01FA01 |
D02069 | ATROPINE SULFATE | ATROPINE SULFATE | |||
| - | Digoxin | C01AA05 | D00298 | LANOXIN | DIGOSIN | |||
| A1 | - | Adenosine | C01EB10 | D02300 | ADENOSINE | ATP, ADETPHOS | ||
| Pump | Na+, K+-, ATPase | - | Digoxin | C01AA05 | D00298 | LANOXIN | DIGOSIN | |
| Other | Class III | Dofetilide | C01BD04 | D00647 | TIKOSYN | |||
| Class II | Alprenolol | C07AA01 | D01182 | SKAJILOL | ||||
| Class II | Nadolol | C07AA12 | D00432 | CORGARD | NADIC | |||
| Class II | Metoprolol | C07AB02 | D00601 | LOPRESSOR | SELOKEN, LOPRESOR | |||
| Class II | Atenolol | C07AB03 | D00235 | TENORMIN | TENORMIN | |||
| Class II | Acebutolol | C07AB04 | D00597 | SECTRAL | ACETANOL | |||
| Class II | Esmolol | C07AB09 | D00644 | BREVIBLOC | BREVIBLOC | |||
| - | Magnesium sulfate | A06AD04 A12CC02 B05XA05 D11AX05 V04CC02 |
D01108 | MAGNESIUM SULFATE | MAGNESIUM SULFATE | |||
| Class III | Ibutilide | C01BD05 | D00648 | CORVERT | ||||
| Class II | Carteolol | C07AA15 S01ED05 |
D00599 | CARTEOLOL HYDROCHLORIDE | MIKELAN | |||
| Category | Title |
| Normal pathway map | Cardiac muscle contraction Vascular smooth muscle contraction |
| Renin-angiotensin system | |
| Adrenergic signaling in cardiomyocytes | |
| Disease pathway map | Hypertrophic cardiomyopathy |
| Dilated cardiomyopathy | |
| Drug structure map | Antiarrhythmic drugs |