UniProt Release 2024_03 The UniProt consortium European Bioinformatics Institute (EBI), SIB Swiss Institute of Bioinformatics and Protein Information Resource (PIR), is pleased to announce UniProt Knowledgebase (UniProtKB) Release 2024_03 (29-May-2024). UniProt (Universal Protein Resource) is a comprehensive catalog of information on proteins. UniProtKB Release 2024_03 consists of 245,482,527 entries (UniProtKB/Swiss-Prot: 571,609 entries and UniProtKB/TrEMBL: 244,910,918 entries) UniRef100 Release 2024_03 consists of 408,368,587 entries UniRef90 Release 2024_03 consists of 190,555,818 entries UniRef50 Release 2024_03 consists of 65,672,468 entries UniParc Release 2024_03 consists of 782,438,918 entries, where 723,563,256 are active and 58,875,662 inactive UniProt databases can be accessed from the web at http://www.uniprot.org and downloaded from http://www.uniprot.org/downloads. Detailed release statistics for TrEMBL and Swiss-Prot sections of the UniProt Knowledgebase can be viewed at http://www.ebi.ac.uk/uniprot/TrEMBLstats/ and http://web.expasy.org/docs/relnotes/relstat.html respectively.